engleski

In situ synthesis of hydroxyapatite within biodegradable polymer matrix

Tissue engineering requires suitable biocompatible materials which can be used as scaffolds for the seeding with cells for the growth of a new tissue. It was suggested that nanostructured composites on the basis of biodegradable polymers and bioactive ceramics such as hydroxyapatite Ca10(PO4)6(OH)2 possess the ability to simulate the surface and/or chemical properties of bone, allowing for exciting alternatives in the design of prosthesis as well as tissue engineering scaffolds1. In this work nano-hydroxyapatite (nano-HA) is synthesized In situ within biodegradable polymeric matrix from precursors solution (calcium carbonate and ureaphosphate) by sol-gel method with controlling of pH value of solution (ammonia). Composition and structure of prepared biomaterials is studied by XRD , FTIR spectroscopy, TG analysis and SEM microscopy.

hydoxyapatite; biomaterials; biodegradable polymers; tissue engineering

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