Disseminated erythema annulare centrifugum presenting concomitantly with ulcerative colitis (CROSBI ID 585443)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Peternel, Sandra ; Lučin, Ksenija ; Kaštelan, Marija ; Brajac, Ines
engleski
Disseminated erythema annulare centrifugum presenting concomitantly with ulcerative colitis
A 23-year-old female presented with sudden onset of pruritic papular rash. Initial lesions expanded into large erythematous, annular and circinate urticarial lesions with central yellowish coloration, covering the whole trunk and extremities. The patient was underweight with a history of recurrent diarrhea. Family history was significant for malignancy with cases of pancreatic cancer, lung cancer and two cases of lymphoma in close relatives. Lesional skin biopsy revealed focal acanthosis, spongiosis and focal degeneration of basal keratinocytes, dermal edema, perivascular and interstitial infiltrate predominantly composed of eosinophils and some lymphocytes. Laboratory studies revealed microcytic anemia, hypoalbuminemia and elevated CRP. Direct immunofluorescence examination and tumor markers were negative. Stool microscopy and colonoscopy revealed ulcerative colitis. Clinical diagnosis of disseminated erythema annulare centrifugum was made, although the histopathology was not typical. The patient was treated with systemic antihistamine and topical corticosteroid. The cutaneous lesions gradually resolved within 5 weeks, leaving faint residual hyperpigmentations.
erythema annulare centrifugum ; histopathology
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Podaci o prilogu
1
2012.
objavljeno
Podaci o matičnoj publikaciji
70th Annual Meeting of the American Academy of Dermatology Abstract Book
San Diego (CA):
Podaci o skupu
70th Annual Meeting of the American Academy of Dermatology, Gross & Microscopic Dermatology Symposium
predavanje
16.03.2012-20.03.2012
San Diego (CA), Sjedinjene Američke Države