engleski

Brief psychiatric rating scale and clinical global impression in evaluation so symptoms in schizophrenic patients taking typical and atypical antipsychotics

Objective: To measure symptomatic improvement with the Brief Psychiatry Rating Scale (BPRS) and Clinical global impressions (CGI) in schizophrenic patients taking typical and atypical antipsychotics. Methods: BPRS and CGI were used in order to assess symptomatic improvement in 100 patients with paranoid schizophrenia, according to DSM-IV-TR criteria. First assessment was made upon the inclusion, the second assessment was made after 6 months of continuous treatment with typical or atypical antipsychotics. Results: At baseline there was no significant difference between two groups of patients, after 6 months of continuous treatment, patients treated with atypcal antipsychotics scored significantly better in BPRS items regarding emotional withdrawal, depressive mood, uncooperativeness and blunted affect. Conclusion: Results indicate superiority of atypical over typical antipsychotics in reducing negative and general symptoms of schizophrenia.

Brief psychiatric rating scale; Clinical global impression; Schizophrenia

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