engleski

Morphology of astrocytes in subplate in cystic and non-cystic white matter injury of preterm infants

The phenotypic features of astrocytes in SP were analyzed in the frontal lobe. In very preterm infant (24-29 gestation weeks, gw) in cystic lesions GFAP astrocytes displayed a non reactive phenotype (small cell body, thin and short processes) and their density was similar to controls. In non-cystic lesions large GFAP positive astrocytes with numerous long processes were found. In preterm infants (30-35 gw) in cystic lesion astrocytes displayed the same features as in cystic lesion of earlier stage. In non-cystic lesion large GFAP astrocytes display peculiar short hairy phenotype in deep SP. The density of GFAP positive astrocytes was significantly increased in deep and superficial SP.

subplate; astrocyte

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