Multifokalni epiteloidni hemangioendoteliom jetre liječen ortotopnom transplantacijom jetre – prikaz bolesnika (CROSBI ID 181342)
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Podaci o odgovornosti
Kocman, Branislav ; Kardum-Skelin, Ika ; Filipec-Kanižaj, Tajana ; Škegro, Dinko ; Vidas, Željko ; Jadrijević, Stipislav ; Čolić-Cvrlje, Vesna
hrvatski
Multifokalni epiteloidni hemangioendoteliom jetre liječen ortotopnom transplantacijom jetre – prikaz bolesnika
Multifocal epithelioid hemangioendothelioma of the liver is a rare primary tumor with a variable course of disease. A case is presented of a 27-year-old female patient with multiple hepatic lesions on ultrasonography, suspect of metastatic tumor of the liver. Serum tumor markers were not elevated, while clinical examination of the lungs, gastrointestinal and gynecologic systems did not confirm the presence of a primary tumor process. Metastatic tumor and primary hepatocellular tumor were ruled out by fine needle aspiration cytology. Along with a characteristic immunophenotype of the vascular cell endothelium (positive for CD31 and CD34), high proliferation demonstrated by the analysis of argyrophilic nucleolar organization regions (AgNOR) and B. Kocman i sur. Multifokalni epiteloidni hemangioendoteliom jetre liječen ortotopnom transplantacijom jetre Acta Med Croatica, 65 (Supl. 1) (2011) 155-160 160 DNA aneuploidy, cytomorphological pattern suggested the diagnosis of angiosarcoma. Histopathologic finding corresponded to epithelioid hemangioendothelioma. Ten years after orthotopic liver transplantation, the patient is free from disease relapse, with regular follow up testing. Hemangioendothelioma of the liver is characterized by multifocality, which excludes resection ; thus, liver transplantation is the method of choice. Therefore, preoperative diagnostic workup is of utmost importance to differentiate it from other primary and metastatic tumors of the liver.
epiteloidni hemangioendoteliom; citološka punkcija; transplantacija jetre
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engleski
Multifocal epithelioid hemangioendothelioma treated by liver transplantation – case report
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epithelioid hemangioendothelioma; fine needle aspiration cytology; liver transplantation
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