Napredna pretraga

Pregled bibliografske jedinice broj: 565377

Expression of endothelial selectin ligands on human leukocytes following dive. FEBS J 2009 ; 276: 193


Čikeš Čulić, Vedrana; Glavaš, Duška; Markotić, Anita; Valić, Zoran; Kovačić, Nataša; Palada, Ivan; Martinić, Roko; Brešković, Toni; Baković, Darija; Brubakk, Alf O; Dujić, Željko
Expression of endothelial selectin ligands on human leukocytes following dive. FEBS J 2009 ; 276: 193 // FEBS J
Prag, Čehoslovačka: Wiley, 2009. str. 276:193-193 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Expression of endothelial selectin ligands on human leukocytes following dive. FEBS J 2009 ; 276: 193
(Expression of endothelial selectin ligands on human leukocytes following dive)

Autori
Čikeš Čulić, Vedrana ; Glavaš, Duška ; Markotić, Anita ; Valić, Zoran ; Kovačić, Nataša ; Palada, Ivan ; Martinić, Roko ; Brešković, Toni ; Baković, Darija ; Brubakk, Alf O ; Dujić, Željko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
FEBS J / - : Wiley, 2009, 276:193-193

Skup
34th FEBS Congress, Life's Molecular Interactions

Mjesto i datum
Prag, Čehoslovačka, 4-9.07.2009

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Endothelial function; monocyte; sialyl-Lewis x; ultrasound

Sažetak
Lewis x (CD15) and sialyl-Lewis x (CD15s) are granulocyte and monocyte carbohydrate antigens recognized as ligands by endothelial selectins. We assumed that CD15 and CD15s could be sensitive markers for impaired vasodilatation following diving. Using flow-cytometry, we determined CD15+ and CD15s+ peripheral blood mononuclear cells of eight divers, 30 min before and 50 min after a single dive to 54 m for 20 min bottom time. The number of gas bubbles in the right heart was monitored by ultrasound. Gas bubbles were seen in all 8 divers, with the average number of bubbles/cm2 1.9± 1.9. Proportion of CD15+ monocytes increased two fold after dive as well as subpopulation of monocytes highly expressing CD15s, the absolute number of monocytes was slightly but no significantly increased after dive, whereas absolute number of granulocytes was markedly elevated (up to 61%) after dive. There was not correlation between CD15+ monocytes expression and bubbles production (p = , 555 ; r = -, 2471) as well as between monocytes highly expressing CD15s and bubbles production (p = , 288 ; r = , 42983. This suggests that biochemical changes induced by diving primary activate existing monocytes rather than increase the number of monocytes at a time of acute arterial endothelial dysfunction.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Farmacija



POVEZANOST RADA


Projekt / tema
216-2160133-0066 - Patobiokemija glikosfingolipidnih antigena (Anita Markotić, )
216-2160133-0130 - Ronjenje s komprimiranim zrakom i kardiovaskularni sustav (Željko Dujić, )

Ustanove
Medicinski fakultet, Split

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE