Antiphospholipid syndrome and central nervous system (CROSBI ID 179321)
Prilog u časopisu | pregledni rad (stručni)
Podaci o odgovornosti
Mayer, Miroslav ; Cerovec, Mislav ; Radoš, Marko ; Čikeš, Nada
engleski
Antiphospholipid syndrome and central nervous system
Classification criteria, etiology, pathogenesis, major central nervous system (CNS) manifestations of the antiphospholipid syndrome (APS), as well as diagnostic and therapeutic approach are discussed in the article, supported by several MRI findings to illustrate differential complexity of selected topics. Close interplay of inflammation, autoimmunity, coagulation cascade, vasculature bed, neuron physiology and demyelinization in APS is elaborated. Cerebrovascular disease, multiple sclerosis-like syndrome, seizures, cognitive disfunction, headache and migraine, chorea and catastrophic antiphospholipid syndrome (CAPS) are discussed as the most prominent CNS manifestations of the APS.
antiphospholipid syndrome ; APL ; nervous system ; systemic erythematosuslupus
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Podaci o izdanju
112 (7)
2010.
602-608
objavljeno
0929-1717
10.1016/j.clineuro.2010.03.023