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Actinomycosis and osteochondroradionecrosis of hyoid bone and thyroid cartilage

Today, head and neck actinomycosis is a rare clinical entity, and laryngeal actinomycosis is even more unusual. Primary actinomycosis occurs in immunocompromised patients with no head and neck lesions, whereas secondary actinomycosis occurs after trauma, operative procedures and/or radiotherapy, or concurrently with malignant lesions, or other infectious diseases. Osteohondroradionecrosis of hyoid bone and thyroid cartilage is rare and severe complication of combined head and neck carcinoma therapy, and it is known that irradiated bone is highly susceptible to infections. To this date, no cases describing actinomycosis and osteoradionecrosis of the hyoid bone and chondroradionecrosis of the laryngeal cartilage were found. We present a case of osteohondroradionecrosis of hyoid bone and chondroradionecrosis of laryngeal cartilage, both accompanied by actinomycosis, in a 54 year old patient following oropharyngeal carcinoma resection, reconstruction surgery, and postoperative radiotherapy. Clinical manifestations, diagnostic dilemmas and therapeutic options are discussed.

head and neck cancer ; actinomycosis ; osteoradionecrosis ; chondroradionecrosis ; hyoid bone ; thyroid cartilage

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