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Pregled bibliografske jedinice broj: 551307

Comparison of Recommendations on Psychopharmacotherapy from Guidelines for Treatment of Schizophrenia


Kozumplik, Oliver; Uzun, Suzana; Jakovljević, Miro
Comparison of Recommendations on Psychopharmacotherapy from Guidelines for Treatment of Schizophrenia // Collegium antropologicum (2012) (znanstveni, prihvaćen)


CROSBI ID: 551307 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Comparison of Recommendations on Psychopharmacotherapy from Guidelines for Treatment of Schizophrenia

Autori
Kozumplik, Oliver ; Uzun, Suzana ; Jakovljević, Miro

Vrsta, podvrsta
Radovi u časopisima, znanstveni

Izvornik
Collegium antropologicum (2012)

Status rada
Prihvaćen

Ključne riječi
Comparison of Recommendations on Psychopharmacotherapy

Sažetak
The aim of this article was to analyse and compare recommendations from guidelines for treatment of schizophrenia on psychopharmacotherapy of schizophrenia. The guidelines were analysed and compared regarding the initiatiation of antipsychotic treatment, the first choice antipsychotic in the first episode of schizophrenia, the daily dosage of antipsychotic in the first episode of schizophrenia, initiation of treatment with a single antipsychotic, introduction of clozapine in therapy, continuous dosing strategies or intermittent-dose strategies, medications in case of nonadherence, recommendations in case of treatment resistance, and initiation of antidepressant treatment. The investigated guidelines recommend that the treatment of psychotic episode should start as soon as possible, and that atypical antipsychotics (except clozapine) should be the first line of treatment during first episode of schizophrenia. The recommended daily dosages are between 300 and 1000 mg chlorpromazine equivalents for the first-generation antipsychotics in the treatment of an acute symptom episode for a minimum of 6 weeks, whereby the minimum effective dose should be used. Treatment should be initiated and continued with a single antipsychotic, except during short periods of overlap in the case of switching, and in the cases of treatment resistance. Guidelines recommend clozapine as treatment of choice for treatment-resistant schizophrenia. Targeted, intermittent dosage maintenance strategies should not be used routinely in lieu of continuous dosage regimens because of the increased risk of symptom worsening or relapse. In case of nonadherence long-acting injectable antipsychotic medication should be considered. Antidepressants may be added as an adjunct to antipsychotics when syndromal criteria for major depressive episode are met. In conclusion, the investigation showed vast similarities between recommendations from the five investigated guidelines for treatment of schizophrenia, with more differences in the extent of recomendations regarding particular investigated treatment issues.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-1083509-3511 - Nuspojave psihofarmaka u bolesnika s psihotičnim i afektivnim poremećajima (Uzun, Suzana, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
Klinički bolnički centar Zagreb

Profili:

Avatar Url Oliver Kozumplik (autor)

Avatar Url Miro Jakovljević (autor)

Avatar Url Suzana Uzun (autor)

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada

Citiraj ovu publikaciju:

Kozumplik, Oliver; Uzun, Suzana; Jakovljević, Miro
Comparison of Recommendations on Psychopharmacotherapy from Guidelines for Treatment of Schizophrenia // Collegium antropologicum (2012) (znanstveni, prihvaćen)
Kozumplik, O., Uzun, S. & Jakovljević, M. (2012) Comparison of Recommendations on Psychopharmacotherapy from Guidelines for Treatment of Schizophrenia. Prihvaćen za objavljivanje u Collegium antropologicum. [Preprint].
@unknown{unknown, year = {2012}, keywords = {Comparison of Recommendations on Psychopharmacotherapy}, journal = {Collegium antropologicum}, title = {Comparison of Recommendations on Psychopharmacotherapy from Guidelines for Treatment of Schizophrenia}, keyword = {Comparison of Recommendations on Psychopharmacotherapy} }
@unknown{unknown, year = {2012}, keywords = {Comparison of Recommendations on Psychopharmacotherapy}, journal = {Collegium antropologicum}, title = {Comparison of Recommendations on Psychopharmacotherapy from Guidelines for Treatment of Schizophrenia}, keyword = {Comparison of Recommendations on Psychopharmacotherapy} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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