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Pregled bibliografske jedinice broj: 550243

Real-time expression of hTERT in primary melanoma biopsies


Katunarić, Miljenko; Jurišić, Davor; Hadžisejdić, Ita; Kirin, Ivan; Zamolo, Gordana
Real-time expression of hTERT in primary melanoma biopsies // Collegium antropologicum, 34 (2010), 4; 1401-1404 (međunarodna recenzija, članak, znanstveni)


Naslov
Real-time expression of hTERT in primary melanoma biopsies

Autori
Katunarić, Miljenko ; Jurišić, Davor ; Hadžisejdić, Ita ; Kirin, Ivan ; Zamolo, Gordana

Izvornik
Collegium antropologicum (0350-6134) 34 (2010), 4; 1401-1404

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
hTERT; primary melanoma; Real-Time; expression; biopsies

Sažetak
Skin melanoma is by far the most lethal skin cancer, it is unpredictable by nature and presents a severe diagnostic problem. One of the major issues in melanoma diagnostics is to differentiate it with confidence from a dysplastic nevus. Thus, the aim of this study was to evaluate hTERT expression on a spectrum of dermal lesions (from normal skin to primary melanoma) in order to examine its possible role as a diagnostic marker in melanoma diagnostics. In this study we analyzed the expression of hTERT by real-time PCR on 58 freshly obtained biopsy samples (4 samples of normal skin, 12 dermal nevi, 23 dysplastic nevi, 19 primary melanomas). Our results showed slightly greater hTERT expression in dysplastic nevi than melanomas with major data overlap. Considering the given results, hTERT does not seem to be a reliable diagnostic marker for melanoma.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
062-0000000-3545 - Telomerazna aktivnost i imunofenotipske karakteristike limfocita u melanomu kože (Gordana Zamolo, )

Ustanove
Medicinski fakultet, Rijeka

Citiraj ovu publikaciju

Katunarić, Miljenko; Jurišić, Davor; Hadžisejdić, Ita; Kirin, Ivan; Zamolo, Gordana
Real-time expression of hTERT in primary melanoma biopsies // Collegium antropologicum, 34 (2010), 4; 1401-1404 (međunarodna recenzija, članak, znanstveni)
Katunarić, M., Jurišić, D., Hadžisejdić, I., Kirin, I. & Zamolo, G. (2010) Real-time expression of hTERT in primary melanoma biopsies. Collegium antropologicum, 34 (4), 1401-1404.
@article{article, year = {2010}, pages = {1401-1404}, keywords = {hTERT, primary melanoma, Real-Time, expression, biopsies}, journal = {Collegium antropologicum}, volume = {34}, number = {4}, issn = {0350-6134}, title = {Real-time expression of hTERT in primary melanoma biopsies}, keyword = {hTERT, primary melanoma, Real-Time, expression, biopsies} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE