engleski

Determination of ractopamine residues in pigs by ultra performance liquid chromatography tandem mass spectrometry

This book chapter provided additional data on the ractopamine residue excretion and accumulation in pigs. Ractopamine hydrochloride is a xenobiotic that belongs to a large group of ß2-adrenergic agonist compounds which are used in human and veterinary medicine for treatment of lung diseases as bronchodilators, tocolytics and heart tonics. Besides their legal use, these drugs are often misused as growth promoters, to improve carcass composition by decreasing fat to the benefit of muscle mass, gaining higher economic benefit to producers. The aim of investigation described in this chapter was to determine ractopamine residue levels in urine and hair after sub-chronic treatment of pigs with low ractopamine doses using UPLC/MS/MS as a sensitive and reliable analytical method for determination of ractopamine concentrations.

ractopamine, pigs, urine, hair, UPLC-MS/MS

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