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Human papillomavirus infection (HPV) in children: case report of an 18-months-old girl with giant anogenital warts


Kotrulja, Lena; Ožanić-Bulić, Suzana; Grce, Magdalena
Human papillomavirus infection (HPV) in children: case report of an 18-months-old girl with giant anogenital warts // Abstract CD of the 19th Congress of the EADV
Gothenburg, Švedska, 2010. str. 427-427 (poster, međunarodna recenzija, sažetak, stručni)


Naslov
Human papillomavirus infection (HPV) in children: case report of an 18-months-old girl with giant anogenital warts

Autori
Kotrulja, Lena ; Ožanić-Bulić, Suzana ; Grce, Magdalena

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Abstract CD of the 19th Congress of the EADV / - , 2010, 427-427

Skup
19th Congress of the European Academy of Dermatology and Venereology - EADV

Mjesto i datum
Gothenburg, Švedska, 6-10.10.2010

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Children; genital wart; HPV

Sažetak
Anogenital warts in children are uncommon and are of special concern to healthcare providers. The infection may result from vertical transmission of HPV either in utero or during delivery from mother to infant. The virus remains latent for a variable period of time before becoming clinically apparent, therefore the time of infection is difficult to predict. Infection by direct manual contact, or rarely by indirect transmission from fomites may also occur. In addition, sexual abuse in children with anogenital warts has been observed and must be considered. Because it has serious medical, social, and legal implications, an interdisciplinary approach to children and their families is necessary. Case report: An 18-month-old girl presented with giant anogenital warts, confirmed on biopsy as condylomata acuminate. A type-specific polymerase chain reaction (PCR) showed HPV types 6/11 in a child, while her mother's cervical smear sample was positive for HPV types 16 and 18. The urethra swab from the child was positive for Chlamydia trachomatis, while the mother was negative for C. trachomatis infection but positive for Ureaplasma urealitycum. Since the child has been delivered by C-section and the mother has no indication of HPV infection by cytology during pregnancy, the social worker was contacted to gather information from all members of the household and to investigate socially unacceptable behaviour, which might lead to a sexual abuse. Genital samples from other household members revealed no HPV infection. The 18-month-old girl with giant condylomata acuminata was probably infected by non-sexual transmission from family members by innocent contact, e.g. sharing of baths or towels with infected adults, although we have not yet identified the person from whom the girl could have acquired the HPV 6/11 infection or a possible perpetrator.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-0982464-2510 - Promijenjeno stanje DNA-metilacije u HPV-povezanim oštećenjima (Magdalena Grce, )

Ustanove
Institut "Ruđer Bošković", Zagreb,
KBC "Sestre Milosrdnice"