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Pregled bibliografske jedinice broj: 548082

Transplatation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects


Gržetić-Lenac, Renata; Merlak, Maja; Balog, Tihomir; Bobić, Marijana Bilen; Dekaris, Iva
Transplatation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects // Collegium antropologicum, 35 (2011), S2; 167-169 (recenziran, članak, stručni)


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Naslov
Transplatation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects

Autori
Gržetić-Lenac, Renata ; Merlak, Maja ; Balog, Tihomir ; Bobić, Marijana Bilen ; Dekaris, Iva

Izvornik
Collegium antropologicum (0350-6134) 35 (2011), S2; 167-169

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
Cornea; amniotic membrane; ulcus cornea

Sažetak
Amniotic membrane transplantation (AMT) leads to reduction of inflammatory symptoms and causes faster epithelisation in corneal ulcers and persistant epithelial defect. 21 patients with corneal ulcer (n=18) or non-healing epithelial defect (n=3) unresponsive to conventional treatment were included in the study. All patients were treated by AMT. Corneal epithelial cells in patients suffering from corneal ulcer secreted 3.51±1.79 of IL-1a, 64.27±31.53 pg/mL of TNFa and 209.07±201.82 pg/mL of VEGF. Levels of all 3 investigated cytokines were significantly higher as compared to controls (p<0.005). Amniotic membranes that were used contained 775.69±613.98 pg/mL of IL-1ra, 0.036±0.033 pg/mL of sTNF and 175.01±166.63 pg/mL of VEGF-R. Supporting effect of the AMT could be explained by the fact that AM secretes its natural antinflammatory antagonists IL-1ra, sTNF and VEGF-R.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
098-0000000-0222 - Imunologija oka (Dekaris, Iva, MZOS ) ( POIROT)
098-0982464-1647 - Sustav citokroma P450 i pojava tumora u starenju i oksidacijskom stresu (Balog, Tihomir, MZOS ) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Tihomir Balog (autor)

Avatar Url Renata Gržetić-Lenac (autor)

Avatar Url Iva Dekaris (autor)

Avatar Url Maja Merlak (autor)

Poveznice na cjeloviti tekst rada:

Hrčak

Citiraj ovu publikaciju:

Gržetić-Lenac, Renata; Merlak, Maja; Balog, Tihomir; Bobić, Marijana Bilen; Dekaris, Iva
Transplatation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects // Collegium antropologicum, 35 (2011), S2; 167-169 (recenziran, članak, stručni)
Gržetić-Lenac, R., Merlak, M., Balog, T., Bobić, M. & Dekaris, I. (2011) Transplatation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects. Collegium antropologicum, 35 (S2), 167-169.
@article{article, year = {2011}, pages = {167-169}, keywords = {Cornea, amniotic membrane, ulcus cornea}, journal = {Collegium antropologicum}, volume = {35}, number = {S2}, issn = {0350-6134}, title = {Transplatation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects}, keyword = {Cornea, amniotic membrane, ulcus cornea} }
@article{article, year = {2011}, pages = {167-169}, keywords = {Cornea, amniotic membrane, ulcus cornea}, journal = {Collegium antropologicum}, volume = {35}, number = {S2}, issn = {0350-6134}, title = {Transplatation of Amniotic Membrane in Corneal Ulcers and Persistant Epithelial Defects}, keyword = {Cornea, amniotic membrane, ulcus cornea} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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