Large volume leukapheresis : Efficacy and safety of processing patient's total blood volume six times (CROSBI ID 177536)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Bojanić, Ines ; Dubravčić, Klara ; Batinić, Drago ; Golubić Čepulić, Branka ; Mazić, Sanja ; Hren, Darko ; Nemet, Damir ; Labar, Boris
engleski
Large volume leukapheresis : Efficacy and safety of processing patient's total blood volume six times
Large-volume leukapheresis (LVL) differs from standard leukapheresis by increased blood flow and an altered anticoagulation regimen. An open issue is to what degree a further increase in processed blood volume is reasonable in terms of higher yields and safety. In 30 LVL performed in patients with hematologic malignancies, 6 total blood volumes were processed. LVL resulted in a higher CD34+ cell yield without a change in graft quality. Although a marked platelet decrease can be expected, LVL is safe and can be recommended as the standard procedure for patients who mobilize low numbers of CD34+ cells and when high number of CD34+ cells are required.
large volume ; leukapheresis ; CD34+ cell
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Podaci o izdanju
44 (2)
2011.
139-147
objavljeno
1473-0502
10.1016/j.transci.2011.01.005
Povezanost rada
Kliničke medicinske znanosti