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Alpha-1-antitrypsin deficiency : from detection to therapy (CROSBI ID 89626)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Dodig, Slavica ; Čepelak, Ivana ; Raos, Miljenko Alpha-1-antitrypsin deficiency : from detection to therapy // Acta pharmaceutica, 50 (2000), 1; 1-16-x

Podaci o odgovornosti

Dodig, Slavica ; Čepelak, Ivana ; Raos, Miljenko

engleski

Alpha-1-antitrypsin deficiency : from detection to therapy

Inherited deficiency of alpha-1-antitrypsin is one of the best know abnormalities affecting the lungs. DNA sequence of the responsible gene has been identified, and the gene has been cloned. Genetically engineered alpha-1-antitrypsin has been synthesised and treatment with synthetic protein has been initiated. Many questions remain. The future will clear out the pathogenesis of liver diseases, replaceable, prophylactic and inhalant therapy for specific and nonspecific protection of lung. Early dection of alpha-1-antitrypsin deficiency as well as drug administration are very important for clinical practice. The patient must be educated about environmental control to avoid or eliminate factors that induce lung diseases.

alpha-1-antitrypsin; lung; disease; liver disease

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Podaci o izdanju

50 (1)

2000.

1-16-x

objavljeno

1330-0075

Povezanost rada

Temeljne medicinske znanosti

Indeksiranost