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Illegal drugs and therapeutic opiates in the wastewaters of the city of Zagreb – estimation of collective consumption and comparison with epidemiological data


Terzić, Senka; Senta, Ivan; Ahel, Marijan
Illegal drugs and therapeutic opiates in the wastewaters of the city of Zagreb – estimation of collective consumption and comparison with epidemiological data // Characterization of hazardous chemical contamination-from environmental chemistry and toxicology to risk assessment / Ahel, Marijan ; Smital, Tvrtko (ur.).
Zagreb: Institute Ruđer Bošković, 2010. str. 19-19 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Illegal drugs and therapeutic opiates in the wastewaters of the city of Zagreb – estimation of collective consumption and comparison with epidemiological data

Autori
Terzić, Senka ; Senta, Ivan ; Ahel, Marijan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Characterization of hazardous chemical contamination-from environmental chemistry and toxicology to risk assessment / Ahel, Marijan ; Smital, Tvrtko - Zagreb : Institute Ruđer Bošković, 2010, 19-19

ISBN
978-953-6690-85-5

Skup
NATO SfP 982590 project workshop

Mjesto i datum
Dubrovnik, Hrvatska, 23-26.09.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Illicit drugs; wastewater; sewage epidemiology

Sažetak
A method employing solid-phase extraction (SPE) and liquid chromatography- tandem mass spectrometry (LC-MS-MS) was developed for a simultaneous determination of trace levels of ten selected drug target residues (DTRs) in untreated (RW) and biologically treated (SE) wastewater. The method was applied to study the occurrence and elimination of selected psychoactive substances in the central wastewater treatment plant of the city of Zagreb during a period of 8 months. The concentrations of all measured DTRs in untreated wastewater were rather low and never exceeded 0.5 µg/L. The average concentrations (n = 39) of individual DTRs were rather different and were in a range from 6.5±6.6 ng/L (amphetamine) to 294±83 ng/L (morphine). The highest average elimination efficiency was achieved for morphine (77±11%) and 6-acetyl morphine (78±13%), while rather low and highly variable elimination was achieved for EDDP (3±17%) and methadone (26±16%). The consumption of 5 selected illicit drugs, including heroin, cocaine, amphetamine, ecstasy and cannabis, was estimated for the city of Zagreb, based on the representative mass loads of the corresponding DTRs, determined in daily-composite RW samples and the average excretion rates, reported in the literature. The study showed that in Zagreb cannabis (1000 kg/year), heroin (75 kg/year) and cocaine (47 kg/year) were comparatively more frequently used as compared to amphetamine-type drugs (1-3 kg/year). Moreover, the mass loads of stimulating drugs (cocaine, amphetamines) were regularly higher on weekends as compared to weekdays. A comparison of the illicit drug consumption from this study with the epidemiology reports, based on the addict treatment records, suggested a much higher number of addicts than official estimates, in particularly with respect to the cocaine addicts [2].

Izvorni jezik
Engleski

Znanstvena područja
Geologija, Kemija



POVEZANOST RADA


Projekt / tema
098-0982934-2712 - Organski spojevi kao molekulski obilježivači antropogenog utjecaja na okoliš (Marijan Ahel, )

Ustanove
Institut "Ruđer Bošković", Zagreb