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Pregled bibliografske jedinice broj: 543234

Necrotising Sarcoid Granulomatosis of the Spinal Cord : Case Report


Vrbica, Žarko; Boras, Zagorka; Rakušić, Neven; Smojver-Ježek, Silvana; Baričević, Denis; Rakušić, Nika; Alerić, Ivan
Necrotising Sarcoid Granulomatosis of the Spinal Cord : Case Report // Collegium Antropologicum, 34 (2010), 2; 713-717 (podatak o recenziji nije dostupan, prethodno priopćenje, znanstveni)


CROSBI ID: 543234 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Necrotising Sarcoid Granulomatosis of the Spinal Cord : Case Report

Autori
Vrbica, Žarko ; Boras, Zagorka ; Rakušić, Neven ; Smojver-Ježek, Silvana ; Baričević, Denis ; Rakušić, Nika ; Alerić, Ivan

Izvornik
Collegium Antropologicum (0350-6134) 34 (2010), 2; 713-717

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prethodno priopćenje, znanstveni

Ključne riječi
case report; diagnosis; sarcoid granulomatosis

Sažetak
We report a patient who presented with leg weakness and cervical lymphadenopathy. Thoracical magnetic resonance imaging showed an inhomogenously increased signal in the thickened portion of the cord. Multilevel laminectomy and spinal cord biopsy revealed granulomatous infiltrations with necrosis. Review of the histopathological finding established the diagnosis of necrotising sarcoid granulomatosis (NSG) of the spinal medulla, cytological FNA diagnosis of the neck lymph node was granulomatous inflammation with necrosis, but histopathological analysis of the same neck lymph node disclosed granulomatous inflammation without necrosis. On further radiographic chest evaluation mediastinal lymphadenopathy was found. Immunophenotyping of lymphocytes in bronchoalveolar lavage fluid (BALF) was indicative of sarcoidosis. After the administration of corticosteroid therapy the patient’s clinical condition improved, and laryngeal and mediastinal lymph nodes subsided with minor changes remaining in the spinal medulla, which, based upon MR assessment, were considered to be irreversible. To our knowledge, this is the first described case with finding of granulomatous inflammation with and without vasculitis in various organs, consistent with the Churg’s study who believes NSG to be a histological variant of sarcoidosis.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekti:
108-1080114-0014 - Molekularna detekcija mikroorganizama: utjecaj na uporabu antimikrobnih lijekova (Plečko, Vanda, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju:

Vrbica, Žarko; Boras, Zagorka; Rakušić, Neven; Smojver-Ježek, Silvana; Baričević, Denis; Rakušić, Nika; Alerić, Ivan
Necrotising Sarcoid Granulomatosis of the Spinal Cord : Case Report // Collegium Antropologicum, 34 (2010), 2; 713-717 (podatak o recenziji nije dostupan, prethodno priopćenje, znanstveni)
Vrbica, Ž., Boras, Z., Rakušić, N., Smojver-Ježek, S., Baričević, D., Rakušić, N. & Alerić, I. (2010) Necrotising Sarcoid Granulomatosis of the Spinal Cord : Case Report. Collegium Antropologicum, 34 (2), 713-717.
@article{article, author = {Vrbica, \v{Z}arko and Boras, Zagorka and Raku\v{s}i\'{c}, Neven and Smojver-Je\v{z}ek, Silvana and Bari\v{c}evi\'{c}, Denis and Raku\v{s}i\'{c}, Nika and Aleri\'{c}, Ivan}, year = {2010}, pages = {713-717}, keywords = {case report, diagnosis, sarcoid granulomatosis}, journal = {Collegium Antropologicum}, volume = {34}, number = {2}, issn = {0350-6134}, title = {Necrotising Sarcoid Granulomatosis of the Spinal Cord : Case Report}, keyword = {case report, diagnosis, sarcoid granulomatosis} }
@article{article, author = {Vrbica, \v{Z}arko and Boras, Zagorka and Raku\v{s}i\'{c}, Neven and Smojver-Je\v{z}ek, Silvana and Bari\v{c}evi\'{c}, Denis and Raku\v{s}i\'{c}, Nika and Aleri\'{c}, Ivan}, year = {2010}, pages = {713-717}, keywords = {case report, diagnosis, sarcoid granulomatosis}, journal = {Collegium Antropologicum}, volume = {34}, number = {2}, issn = {0350-6134}, title = {Necrotising Sarcoid Granulomatosis of the Spinal Cord : Case Report}, keyword = {case report, diagnosis, sarcoid granulomatosis} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka::


  • MEDLINE





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