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Pregled bibliografske jedinice broj: 543057

Comparison of antihyperglycemic effects of creatine and glibenclamide in type II diabetic patients


Ročić, B; Znaor, A; Ročić, P; Weber, D; Vučić Lovrenčić, M
Comparison of antihyperglycemic effects of creatine and glibenclamide in type II diabetic patients // Wiener medizinische Wochenschrift, 161 (2011) doi:10.1007/s10354-011-0905-7 (međunarodna recenzija, članak, znanstveni)


Naslov
Comparison of antihyperglycemic effects of creatine and glibenclamide in type II diabetic patients

Autori
Ročić, B ; Znaor, A ; Ročić, P ; Weber, D ; Vučić Lovrenčić, M

Izvornik
Wiener medizinische Wochenschrift (1563-258X) 161 (2011);

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Creatine; glibenclamide; glucose; insulin; type II

Sažetak
This study compares the effects of glibenclamide and creatine in type II diabetics. In a 14-day symmetrically randomized crossover trial recently detected type II diabetics received either creatine (3 g) or glibenclamide (3.5 mg) for five successive days, followed by two days of washout, and crossover to the opposite treatment. Glucose, insulin, c-peptide, and creatine were measured. Creatine and glibenclamide decreased glucose concentrations vs. basal glucose [15, 60, 90, 120, 180, and 240 min ; mol/l]: 12.60.83 vs. 12.20.56 vs. 12.10.57, 15.30.63 vs. 13.5 0.70a vs. 13.00.57a, 14.80.57 vs. 13.80.59a vs. 13.40.46a, 14.60.61 vs. 12.30.49b vs. 12.40.61a, 12.80.76 vs. 10.0 0.40c vs. 10.30.41c, and 11.40.67 vs. 8.30.40c vs. 8.50.36c ; (ap < 0.05 ; bp < 0.01 ; cp < 0.001 vs. basal glucose). Treatment with both creatine and glibenclamide increased insulin and c-peptide concentrations after 120 and 240min (p < 0.05 and p < 0.01). At the doses applied short-term treatment with creatine and glibenclamide elicits similar glucose lowering effects.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
045-1191348-0139 - Biomolekule guanidinskog tipa u šećernoj bolesti (Marijana Vučić Lovrenčić, )

Ustanove
Klinika za dijabetes, endokrinologiju i bolesti metabolizma Vuk Vrhovac

Citiraj ovu publikaciju

Ročić, B; Znaor, A; Ročić, P; Weber, D; Vučić Lovrenčić, M
Comparison of antihyperglycemic effects of creatine and glibenclamide in type II diabetic patients // Wiener medizinische Wochenschrift, 161 (2011) doi:10.1007/s10354-011-0905-7 (međunarodna recenzija, članak, znanstveni)
Ročić, B., Znaor, A., Ročić, P., Weber, D. & Vučić Lovrenčić, M. (2011) Comparison of antihyperglycemic effects of creatine and glibenclamide in type II diabetic patients. Wiener medizinische Wochenschrift, 161 doi:10.1007/s10354-011-0905-7.
@article{article, year = {2011}, DOI = {DOI 10.1007/s10354-011-0905-7}, keywords = {Creatine, glibenclamide, glucose, insulin, type II}, journal = {Wiener medizinische Wochenschrift}, doi = {DOI 10.1007/s10354-011-0905-7}, volume = {161}, issn = {1563-258X}, title = {Comparison of antihyperglycemic effects of creatine and glibenclamide in type II diabetic patients}, keyword = {Creatine, glibenclamide, glucose, insulin, type II} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • EMBASE (Excerpta Medica)
  • MEDLINE
  • SCOPUS


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