Mn-SOD and Chronic Inflammation of Gastric Mucosa (CROSBI ID 176660)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Dovhanj, Jasna ; Švagelj, Dražen ; Smolić, Martina ; Smolić, Robert ; Marić, Ivana
engleski
Mn-SOD and Chronic Inflammation of Gastric Mucosa
The involvement of reactive oxygen species in the inflammatory tissue destruction is well known. Significant changes in the activity and expression of several isoforms of superoxide dismutase were observed in the human gastric disease. Mn-SOD attracted the attention of researchers because of its inducibility by oxidative stress. There is increasing evidence that oxidative stress plays a role in the progression of mucosal damage leading to gastric cancer. The evaluation of possible modulation of Mn-SOD activity during chronic inflammation of gastric mucosa could reveal whether its assessment is important to prevent the accumulation of gastric epithelial cell damage and thereby reduce the risk of gastric carcinoma.
free radical; gastric mucosa; inflammation; oxidative stress; ROS; SOD
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Podaci o izdanju
9 (4)
2010.
347-354
objavljeno
1871-5230
1875-614X