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Mn-SOD and Chronic Inflammation of Gastric Mucosa


Dovhanj, Jasna; Švagelj, Dražen; Smolić, Martina; Smolić, Robert; Marić, Ivana
Mn-SOD and Chronic Inflammation of Gastric Mucosa // Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 9 (2010), 4; 347-354 (međunarodna recenzija, članak, znanstveni)


Naslov
Mn-SOD and Chronic Inflammation of Gastric Mucosa

Autori
Dovhanj, Jasna ; Švagelj, Dražen ; Smolić, Martina ; Smolić, Robert ; Marić, Ivana

Izvornik
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry (1871-5230) 9 (2010), 4; 347-354

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Free radical; gastric mucosa; inflammation; oxidative stress; ROS; SOD

Sažetak
The involvement of reactive oxygen species in the inflammatory tissue destruction is well known. Significant changes in the activity and expression of several isoforms of superoxide dismutase were observed in the human gastric disease. Mn-SOD attracted the attention of researchers because of its inducibility by oxidative stress. There is increasing evidence that oxidative stress plays a role in the progression of mucosal damage leading to gastric cancer. The evaluation of possible modulation of Mn-SOD activity during chronic inflammation of gastric mucosa could reveal whether its assessment is important to prevent the accumulation of gastric epithelial cell damage and thereby reduce the risk of gastric carcinoma.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
219-2192190-2182 - Osobitosti koštane pregradnje u bolesnika s urolitijazom (Jasminka Milas-Ahić, )
219-2192190-2186 - Prevencija stvaranja i recidiva mokraćnih kamenca (Antun Tucak, )

Ustanove
Medicinski fakultet, Osijek

Časopis indeksira:


  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • EMBASE (Excerpta Medica)