Paediatric pneumococcal disease in Central Europe (CROSBI ID 176305)
Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija
Podaci o odgovornosti
Prymula, R. ; Chlibek, R. ; Ivaskeviciene, I. ; Mangarov, A. ; Mészner, Z. ; Perenovska, P. ; Richter, Darko ; Salman, N. ; Simurka, P. ; Tamm, E. ; Tešović, Goran ; Urbancikova, I. ; Usonis, V.
engleski
Paediatric pneumococcal disease in Central Europe
Streptococcus pneumoniae causes considerable global paediatric morbidity and mortality, despite the availability of safe and effective pneumococcal conjugate vaccines (PCVs). To justify the introduction of PCVs, accurate information on the burden of disease is required. Here, we present an appraisal of the pneumococcal epidemiological situation in 11 Central European countries. The data are based on study findings presented at the 12th Central European Vaccine Advisory Group (CEVAG) meeting, held on 21-22 May 2010 in Sofia, Bulgaria, and a literature review of the PubMed database using the search terms 'pneumococcal' or 'Streptococcus pneumoniae', in combination with 'otitis media', 'pneumonia', 'meningitis' or 'bacteraemia/sepsis', and '[Central European country name]'. The incidence of pneumococcal disease appears to be lower in Central Europe than previously reported for Europe as a whole, with the highest risk in infants aged 0-2 years. The fatality rates in the under fives from invasive infections are up to 40%. A paucity of comprehensive country-specific data on pneumococcal disease burden arises from the lack of homogenous surveillance programmes. Standardised, active surveillance systems are required for the accurate evaluation of the pneumococcal disease burden in the region. Only then can the need for vaccination be addressed.
Paediatric pneumococcal disease; Central Europe
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Podaci o izdanju
30 (11)
2011.
1311-1320
objavljeno
0934-9723
10.1007/s10096-011-1241-y
Povezanost rada
Kliničke medicinske znanosti