Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Level of vascular endothelial growth factor in recurrent aphthous ulceration (CROSBI ID 476815)

Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija

Brozović-Sistig, Suzana ; Vučićević-Boras, Vanja ; Kleinheinz, Josef ; Joos, Uli ; Jukić, Silvana Level of vascular endothelial growth factor in recurrent aphthous ulceration // IADR CED/NEF / Academia Medica Varsoviensis (ur.). Varšava: Academia Medica Varsoviensis, 2000. str. 228-x

Podaci o odgovornosti

Brozović-Sistig, Suzana ; Vučićević-Boras, Vanja ; Kleinheinz, Josef ; Joos, Uli ; Jukić, Silvana

engleski

Level of vascular endothelial growth factor in recurrent aphthous ulceration

Saliva contains biologically active proteins such as several different growth factors, cytokines and prostaglandins. This study investigated salivary level of vascular endothelial growth factor in 30 patients with minor and major recurrent aphthous ulceration (RAU) and 27 age matched healthy controls. VEGF was determined by ELISA in resting whole saliva of all participants. The development of recurrent aphthous ulceration was divided into stages: (1) early prodromal stage (mucosal redness or erosion), (2) active disease (frank ulceration) and (3) remission stage. Significantly lower level of salivary VEGF (p<0,001) was found in patients with major RAU during active disease when compared to the controls. Statistical analysis was done by Student t test. The mean ąSD were 327, 02ą113,05 pg/ml in acute stage of major RAU and 1488,88ą605,38 pg/ml in healthy controls. Salivary VEGF showed stage dependent alterations as well as variations regarding the type of ulcers. The VEGF concentration decreased significantly during the active stage of a disease and increased during the remission period in patients with major RAU. No differences in salivary VEGF in patients with acute minor RAU as well as during remission period when compared to controls was found. In conclusion, diminution of salivary VEGF was observed in acute stage of major RAU suggesting active involvement of this compound in the pathogenesis of the disease. It is also suggested that VEGF may also have cytoprotective role in homeostasis of oral cavity.

vascular endothelial factor; aphthous ulcers

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

228-x.

2000.

objavljeno

Podaci o matičnoj publikaciji

IADR CED/NEF

Academia Medica Varsoviensis

Varšava: Academia Medica Varsoviensis

Podaci o skupu

The 4th Joint Meeting of the IADR CED/NOF

poster

24.08.2000-27.08.2000

Varšava, Poljska

Povezanost rada

Dentalna medicina