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Pregled bibliografske jedinice broj: 537041

Alkaline comet assay and micronucleus test parameters in children exposed to diagnostic x-ray examination


Gajski, Goran; Milković, Đurđica; Ranogajec-Komor, Mária; Miljanić, Saveta; Knežević, Željka; Beck, Natko; Gerić, Marko; Garaj-Vrhovac, Vera
Alkaline comet assay and micronucleus test parameters in children exposed to diagnostic x-ray examination // Proceedings of the 8th Symposium of the Croatian Radiation Protection Association / Krajcar Bronić, Ines ; Kopjar, Nevenka ; Milić, Mirta ; Branica, Gina (ur.).
Zagreb: Denona, 2011. str. 129-133 (predavanje, domaća recenzija, cjeloviti rad (in extenso), znanstveni)


CROSBI ID: 537041 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Alkaline comet assay and micronucleus test parameters in children exposed to diagnostic x-ray examination

Autori
Gajski, Goran ; Milković, Đurđica ; Ranogajec-Komor, Mária ; Miljanić, Saveta ; Knežević, Željka ; Beck, Natko ; Gerić, Marko ; Garaj-Vrhovac, Vera

Vrsta, podvrsta i kategorija rada
Radovi u zbornicima skupova, cjeloviti rad (in extenso), znanstveni

Izvornik
Proceedings of the 8th Symposium of the Croatian Radiation Protection Association / Krajcar Bronić, Ines ; Kopjar, Nevenka ; Milić, Mirta ; Branica, Gina - Zagreb : Denona, 2011, 129-133

ISBN
978-953-96133-7-0

Skup
8th Symposium of the Croatian Radiation Protection Association

Mjesto i datum
Krk, Hrvatska, 13-15.04.2011

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Domaća recenzija

Ključne riječi
Child population; X-ray examination; Dosimetry; Comet assay; Micronucleus assay; Genome damage

Sažetak
Understanding the risks of low doses of radiation is an important aspect in the risk benefit analysis in pediatric populations. To provide the best care for the young patients the effects of ionizing radiation should be minimized. Since children with pulmonary diseases are at a relatively greater cancer risk as the radiological exposure can be intensive in these patients, present study aimed to evaluate application of different dosimetry systems and comet and micronucleus assay in monitoring children population exposed to diagnostic X-rays examination. The study comprised a random sample of 18 children, all with pulmonary diseases, such as pneumonia, bronchitis, asthma and suspected tuberculosis. Absorbed dose measurements were conducted for posterior-anterior projection on the forehead, thyroid gland, gonads, chest and back. Doses were measured using thermoluminescence and radiophotoluminescent dosimetry systems. It was shown that after diagnostic X-rays, the mean total number of all measured parameters was significantly higher than prior to diagnostic procedure. These results suggest that even low-dose diagnostic X-ray exposure may induce damaging effect to the cell and DNA molecule of exposed children. Thus it would be useful to conduct more research in pediatric diagnostics to minimize the potential damage and maintain the optimal benefit for the patients.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija



POVEZANOST RADA


Projekti:
022-0222148-2125 - Mutageni i antimutageni u ekogenetičkim istraživanjima (Garaj-Vrhovac, Vera, MZOS ) ( POIROT)
098-0982904-2954 - Fizičko-kemijski učinci ionizirajućih zračenja u materijalima (Mihaljević, Branka, MZOS ) ( POIROT)
277-2770966-0962 - Učinci radioloških dijagnostičkih postupaka pri pregledu dišnih putova u djece (Milković, Đurđica, MZOS ) ( POIROT)

Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Institut "Ruđer Bošković", Zagreb,
Dječja bolnica Srebrnjak


Citiraj ovu publikaciju:

Gajski, Goran; Milković, Đurđica; Ranogajec-Komor, Mária; Miljanić, Saveta; Knežević, Željka; Beck, Natko; Gerić, Marko; Garaj-Vrhovac, Vera
Alkaline comet assay and micronucleus test parameters in children exposed to diagnostic x-ray examination // Proceedings of the 8th Symposium of the Croatian Radiation Protection Association / Krajcar Bronić, Ines ; Kopjar, Nevenka ; Milić, Mirta ; Branica, Gina (ur.).
Zagreb: Denona, 2011. str. 129-133 (predavanje, domaća recenzija, cjeloviti rad (in extenso), znanstveni)
Gajski, G., Milković, Đ., Ranogajec-Komor, M., Miljanić, S., Knežević, Ž., Beck, N., Gerić, M. & Garaj-Vrhovac, V. (2011) Alkaline comet assay and micronucleus test parameters in children exposed to diagnostic x-ray examination. U: Krajcar Bronić, I., Kopjar, N., Milić, M. & Branica, G. (ur.)Proceedings of the 8th Symposium of the Croatian Radiation Protection Association.
@article{article, author = {Gajski, Goran and Milkovi\'{c}, \DJur\djica and Ranogajec-Komor, M\'{a}ria and Miljani\'{c}, Saveta and Kne\v{z}evi\'{c}, \v{Z}eljka and Beck, Natko and Geri\'{c}, Marko and Garaj-Vrhovac, Vera}, year = {2011}, pages = {129-133}, keywords = {Child population, X-ray examination, Dosimetry, Comet assay, Micronucleus assay, Genome damage}, isbn = {978-953-96133-7-0}, title = {Alkaline comet assay and micronucleus test parameters in children exposed to diagnostic x-ray examination}, keyword = {Child population, X-ray examination, Dosimetry, Comet assay, Micronucleus assay, Genome damage}, publisher = {Denona}, publisherplace = {Krk, Hrvatska} }
@article{article, author = {Gajski, Goran and Milkovi\'{c}, \DJur\djica and Ranogajec-Komor, M\'{a}ria and Miljani\'{c}, Saveta and Kne\v{z}evi\'{c}, \v{Z}eljka and Beck, Natko and Geri\'{c}, Marko and Garaj-Vrhovac, Vera}, year = {2011}, pages = {129-133}, keywords = {Child population, X-ray examination, Dosimetry, Comet assay, Micronucleus assay, Genome damage}, isbn = {978-953-96133-7-0}, title = {Alkaline comet assay and micronucleus test parameters in children exposed to diagnostic x-ray examination}, keyword = {Child population, X-ray examination, Dosimetry, Comet assay, Micronucleus assay, Genome damage}, publisher = {Denona}, publisherplace = {Krk, Hrvatska} }




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