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Sialochemistry in Patients with Oral Lichen Planus (CROSBI ID 175958)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Vučićević Boras, Vanja ; Rogić, Dunja ; Brailo, Vlaho ; Vidović Juras, Danica ; Glažar, Irena ; Muhvić-Urek, Miranda Sialochemistry in Patients with Oral Lichen Planus // Acta stomatologica Croatica, 45 (2011), 3; 184-189

Podaci o odgovornosti

Vučićević Boras, Vanja ; Rogić, Dunja ; Brailo, Vlaho ; Vidović Juras, Danica ; Glažar, Irena ; Muhvić-Urek, Miranda

engleski

Sialochemistry in Patients with Oral Lichen Planus

Objective: It is well known that certain salivary constituents might be disturbed in patients suffering from oral lichen planus (OLP), however, the results of the published studies are inconsistent. The aim of this study was to assess the concentrations of salivary analytes because most of them are part of salivary enzymes which maintain integrity of the oral mucosa which is compromised in OLP patients. Materials and Methods: In 25 patients with OLP (73±1.4 yrs) and in the 24 controls (24±3.7yrs) levels of total proteins, amylase, salivary magnesium, calcium, copper, chloride, phosphate, potassium and sodium were determined. Total proteins were determined by pyrogalol colorimetric method. Amylase levels were determined by continued colorimetric method. Salivary sodium, potassium and chloride were determined by indirect potentiometry whereas salivary copper and magnesium were determined by atomic absorption spectrophotometry whereas phosphates were determined by colorimetric method with use of molybdate. Statistical analysis was performed by use of χ2 test, Mann Whitney U test, analysis of covariance and Spearman´s correlation. Results: Significantly higher concentration of salivary chloride was detected in OLP patients in comparison to the controls (p=0.025). Furthermore, when the obtained results for salivary analytes were adjusted with respect to the salivary flow rate, increased levels of salivary potassium, sodium, chloride and total proteins were found in patients with OLP when compared to the controls (p=0.622 ; p=0.504 ; p=0.600 ; p=0.586). Concentrations of salivary analytes were not affected by smoking habit. Conclusions: Increased levels of salivary sodium, potassium and chloride are probably a result of significant differences in salivary flow rate between patients with OLP and controls and do not indicate increased salivary antimicrobial activity.

Saliva ; Lichen Planus ; Salivary Proteins and Peptides

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Podaci o izdanju

45 (3)

2011.

184-189

objavljeno

0001-7019

1846-0410

Povezanost rada

Dentalna medicina

Poveznice
Indeksiranost