engleski

SOD-like activity in asthenozoospermia: In vitro inhibition by zinc

The activity of sperm superoxide dismutase (Cu,Zn SOD)is not fully elucidated in asthenozoospermia, characterised by normal spermatozoa concnetration but with reduced motility. The aim of this study was to evaluate the SOD-like activity as well as in vitro effect of zinc on its activity in astheno and normozoospermia. SOD-like activity was determined in two Percoll fractions of 18 normozoospermic (>20 x 106 sperms/ml; motility> 40%)and 12 asthenozoospermic subjects (motility <40%). In vitro effect of zinc was assessed on unfractionated spermatozoa of 27 normo-and 18asthenozoospermic males. SOD-like activity was measured using RanSod test. SOD-like activity was significantly elevated in 40% Percoll fraction of asthenozoospermic when compared to normozoospermic samples (p<0.03)

SOD-like activity; Zinc; asthenozoospermia

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