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Pregled bibliografske jedinice broj: 532626

From Dust To Dust: Forensic Dna Analysis


Primorac, Dragan; Marjanović, Damir; Škaro, Vedrana; Budimlija, Zoran; Definis-Gojanović, Marija; Sutlović, Davorka; Bosnar, Alan; Marcikić, Mladen; Anđelinović, Šimun
From Dust To Dust: Forensic Dna Analysis // 7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine: final program and abstracts
Zagreb: International Society for Applied Biological Sciences, 2011. str. 67-67 (predavanje, međunarodna recenzija, sažetak, znanstveni)


Naslov
From Dust To Dust: Forensic Dna Analysis

Autori
Primorac, Dragan ; Marjanović, Damir ; Škaro, Vedrana ; Budimlija, Zoran ; Definis-Gojanović, Marija ; Sutlović, Davorka ; Bosnar, Alan ; Marcikić, Mladen ; Anđelinović, Šimun

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
7th ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine: final program and abstracts / - Zagreb : International Society for Applied Biological Sciences, 2011, 67-67

Skup
7th ISABS Conference in Forensic, Anthropologic and Medical Genetics

Mjesto i datum
Bol, Island of Brač, Croatia, 20-24.07. 2011

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Identification; bones; STRs; Croatia; Bosnia and Herzegovina

Sažetak
The primary value of DNA profiling significantly increased over the last fifteen years due to introduction of short tandem repeat (STR) loci in routine paternity testing, forensic work and identification of victims of mass disaster. Different methods of forensic DNA testing (known as DNA fingerprinting) have been widely established and accepted as standard procedures of investigation. This lecture presents the experience of the last eighteen years of identification of missing persons in Bosnia and Croatia. The data show that current protocols and procedures optimized for relatively fresh bones and teeth can be used in analysis of much older samples without significant modification. Also, introduction of new technologies (e.g., miniSTR assay) can help recover information from degraded DNA samples that typically result in partial profiles and total loss of information from regular STR amplicons. This approach has already been used in the analysis of highly degraded samples like those from the victims of World Trade Center terrorist attacks and WWII. Now the use of this scientific approach has been proven even for the two millenia old bone samples. In collaboration with Roche Molecular Systems recently we used a new generation of mtDNA strips and were able to get full profiles from several century old bones even in a cases where STR amplification completely failed.

Izvorni jezik
Engleski

Znanstvena područja
Biologija