engleski

Bioactivity of 14C-labeled endotoxin in aggregates, shed blebs and whole bacteria: Potency comparison in the LAL assay, cell cultures, and mouse bioassays

It is unknown if endotoxin reactivity in the LAL assay varies by its presentation or if this parallels differences in potency in vitro and in vivo.We compared endotoxin responses in the LAL assay, in cell cultures and in vivo when presented in different forms.

N. meningitidis; LOS aggregates; shed blebbs; whole bacteria

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