engleski

Carotid Artery Stiffness in Type 2 Diabetes Patients

Purpose: Prevalence of type 2 diabetes mellitus (DM) is increasing. DM is a major risk factor for cerebrovascular diseases. Assessment of arterial structure and function, by non-invasive methods, can be used in early detection of vascular complications. Besides intima-media thickness (IMT), beta stiffness index (BSI) was recently recognized as a surrogate marker of atherosclerosis. The aim of this study was to explore BSI in patients with type 2 DM. Material & Methods: Patients with type 2 DM were examined in our Stroke prevention centre by means of ultrasound with a high-resolution echo-tracking system, on Aloka Prosound alpha 7 system equipped with 8MHz probe. IMT of common carotid artery was measured by highresolution B- mode ultrasound imaging. Results: Altogether 32 DM patients (16 female) were examined (mean age 65, 9₠ı, 68, 7 years). Most of patients (26) were hypertensive (142₠ı, 621 over 86₠ı, 69 mmHg) and had increased BMI (31, 1₠ı, 64, 8 kg/m2). Average IMT was 0, 72₠ı, 60, 15 (right CCA) and 0, 76₠ı, 60, 15 (left CCA). Average BSI was 11, 6₠ı, 65, 5 (right CCA) and 11, 8₠ı, 63, 8 (left CCA). IMT was significantly correlated with waist circumference and age, while BSI correlated with systolic blood pressure, waist circumference and heart beat rate. Conclusion: Increased carotid IMT and BSI in type 2 DM patients were registered. Further studies are needed to assess the impact of these parameters on stroke risk and outcome.

carotid artery stiffness; IMT; diabetes mellitus

nije evidentirano