engleski

Nosocomial respiratory syncytial virus infections in Zagreb hospitals

Nosocomial infections with respiratory syncytial virus (RSV) are very common in children’s wards. In the 1985-94 period we examined in several separated studies intrahospital RSV infections in the children’s wards of Zagreb hospitals. RSV infection was documented by detection of virus in nasopharyngeal secretion using specific antibodies in immunofluorescent test and subsequently confirmed by isolation of the virus in cell culture using standard techniques. We thus found virus nosocomial infections to account for 42 /173 (24.3%) of the acute respiratory ill inpatients aged up to 3 years in 1985. Nosocomial RSV infections made up 17/84 (20.2%) of the demonstrated respiratory viral infections. In the 1986/87 season, 20 of the 44 (45.5%) neonates were affected by a proved nosocomial RSV infection. Among RSV-positive neonates 9/20 (45%) had upper respiratory tract infections, 2/20 (10%) bronchiolitis, 4/20 (20%) pneumonia and 4/20 (20%) bronchitis. In the period 1988-94 we looked at RSV lower respiratory tract infections (LRTI) showing 42 patients of the 201( 21%) to have a hospital-acquired RSV- LRTI. Bronchitis was the most common diagnosis 20/42 (47.6%). The largest number of nosocomial infections 19/42 (45.2%) was observed in infants aged up to 6 months. Guidelines for prevention of RSV nosocomial infection are given.

respiratory syncytial virus (RSV); nosocomial infection; parainfluenza virus; adenovirus; influenza virus; guidelines for prevention

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