Napredna pretraga

Pregled bibliografske jedinice broj: 526650

Respiratory health and breath condensate acidity in sawmill workers


Ljubičić Ćalušić, Anita; Varnai, Veda Marija; Čavlović, Anka Ozana; Šegvić Klarić, Maja; Beljo-Lučić, Ružica; Prester, Ljerka; Macan, Jelena
Respiratory health and breath condensate acidity in sawmill workers // International archives of occupational and environmental health, 86 (2013), 7; 815-825 doi:10.1007/s00420-012-0817-x (međunarodna recenzija, članak, znanstveni)


Naslov
Respiratory health and breath condensate acidity in sawmill workers

Autori
Ljubičić Ćalušić, Anita ; Varnai, Veda Marija ; Čavlović, Anka Ozana ; Šegvić Klarić, Maja ; Beljo-Lučić, Ružica ; Prester, Ljerka ; Macan, Jelena

Izvornik
International archives of occupational and environmental health (0340-0131) 86 (2013), 7; 815-825

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Bronchodilator test; EBC pH; moulds; smoking; wood dust

Sažetak
PURPOSE: The aim of the study was to evaluate exhaled breath condensate acidity (EBC pH) as a biomarker of airway response to occupational respiratory hazards present in sawmill. METHODS: Sixty-one sawmill workers in total (26 from Sawmill 1 and 35 from Sawmill 2) provided EBC samples at the beginning and at the end of the working week. Respiratory symptoms, lung function, bronchodilator test and atopy status were assessed. Occupational environment was checked for the levels of respiratory hazards. RESULTS: Airborne dust concentrations were below threshold limit value. Endotoxin in Sawmill 1 and Sawmill 2, and moulds in Sawmill 1 were at the levels able to induce inflammatory response in the airways. Mould levels were 2.5 times higher in Sawmill 1 than in Sawmill 2. Compared to Sawmill 2 workers, lower spirometry values, higher prevalence of dry cough and positive bronchodilator test were found in Sawmill 1 workers. Monday EBC pH values did not differ between sawmills, but declined after one working week in Sawmill 1 workers (from 7.88 to 7.49, P = 0.012) and not in Sawmill 2 workers. Similar results were obtained when only respiratory healthy non-smokers were analysed. Monday-to-Friday change of other respiratory parameters was not observed. CONCLUSION: The results suggest EBC pH as a biomarker of acute respiratory effects related to occupational exposure to respiratory hazards in sawmills, presumably increased mould levels. The effect was present even at subclinical level, namely in respiratory healthy subjects. The long-term health implications remain unclear and should be evaluated in a follow-up study.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita, Drvna tehnologija



POVEZANOST RADA


Projekt / tema
006-0061117-1242 - Mikromicete, interakcije toksičnih metabolita-zdravlje i prevencija (Maja Šegvić Klarić, )
022-0222411-2410 - Alergotoksični učinci čimbenika općeg i radnog okoliša (Jelena Macan, )
068-0682094-2095 - Optimiranje energijskih i ergonomskih čimbenika mehaničke obrade drva (Anka Ozana Čavlović, )

Ustanove
Farmaceutsko-biokemijski fakultet, Zagreb,
Institut za medicinska istraživanja i medicinu rada, Zagreb,
Šumarski fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati