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Pregled bibliografske jedinice broj: 523193

Klinefelter Syndrome and Acute Basophilic Leukemia : Case Report


Ljubić, Nives; Lang, Nada; Kardum-Skelin, Ika; Lasan, Ružica; Dominis, Mara; Perković, Leila; Županić-Krmek, Dubravka; Grgurević-Batinica, Anita
Klinefelter Syndrome and Acute Basophilic Leukemia : Case Report // Collegium antropologicum, 34 (2010), 2; 657-660 (podatak o recenziji nije dostupan, prethodno priopćenje, stručni)


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Naslov
Klinefelter Syndrome and Acute Basophilic Leukemia : Case Report

Autori
Ljubić, Nives ; Lang, Nada ; Kardum-Skelin, Ika ; Lasan, Ružica ; Dominis, Mara ; Perković, Leila ; Županić-Krmek, Dubravka ; Grgurević-Batinica, Anita

Izvornik
Collegium antropologicum (0350-6134) 34 (2010), 2; 657-660

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prethodno priopćenje, stručni

Ključne riječi
Klinefelter syndrome; acute myeloid leukemia; acute basophilic leukemia

Sažetak
Patients with 47, XXY karyotype (Klinefelter syndrome) appear to have increased risk of developing cancer, especially male breast cancer, germ cell tumours and non Hodgkin lymphomas, but rarely acute myeloid leukaemia. We report a patient with acute basophilic leukaemia with 47, XXY karyotype in both the tumour and constitutional cells. Acute basophilic leukaemia is very rare disease comprising less than 1% of all acute myeloid leukaemias. Morphological characteristic of leukaemic blast cells is moderately basophilic cytoplasm containing a variable number of coarse basophilic granules. The most characteristic cytochemical reaction is metachromatic positivity with toluidine blue. Blast are myeloperoxidase negative. Also leukemic blasts express myeloid and monocyte markers. There is no consistent chromosomal abnormality identified in this leukaemia. This is the first reported case of acute basophilic leukaemia in patient with Klinefelter syndrome. In this article the medical history of the patient is given and the possible connection between Klinefelter syndrome and acute myeloid leukaemia is discussed.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Napomena
Rad je kao poster prezentiran na zajednickom skupu 4. hrvatski kongres kliničke citologije s međunarodnim sudjelovanjem, 1. hrvatski simpozij analitičke citologije i 2. hrvatski simpozij citotehnologije s međunarodnim sudjelovanjem, održanom od 11-14.10.2009.g., Split, Hrvatska ; objavljen u Knjizi sažetaka ; Ika Kardum-Skelin, Drago Batinić, Varonika Anić (ur.). - Zagreb : Hrvatsko društvo za kliničku citologiju HLZ, Sekcija za analitičku citologiju, Hrvatska udruga citotehnologa, 2009.



POVEZANOST RADA


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Ustanove
Farmaceutsko-biokemijski fakultet, Zagreb,
Medicinski fakultet, Zagreb,
Klinička bolnica "Sveti Duh",
Klinička bolnica "Dubrava"

Citiraj ovu publikaciju

Ljubić, Nives; Lang, Nada; Kardum-Skelin, Ika; Lasan, Ružica; Dominis, Mara; Perković, Leila; Županić-Krmek, Dubravka; Grgurević-Batinica, Anita
Klinefelter Syndrome and Acute Basophilic Leukemia : Case Report // Collegium antropologicum, 34 (2010), 2; 657-660 (podatak o recenziji nije dostupan, prethodno priopćenje, stručni)
Ljubić, N., Lang, N., Kardum-Skelin, I., Lasan, R., Dominis, M., Perković, L., Županić-Krmek, D. & Grgurević-Batinica, A. (2010) Klinefelter Syndrome and Acute Basophilic Leukemia : Case Report. Collegium antropologicum, 34 (2), 657-660.
@article{article, year = {2010}, pages = {657-660}, keywords = {Klinefelter syndrome, acute myeloid leukemia, acute basophilic leukemia}, journal = {Collegium antropologicum}, volume = {34}, number = {2}, issn = {0350-6134}, title = {Klinefelter Syndrome and Acute Basophilic Leukemia : Case Report}, keyword = {Klinefelter syndrome, acute myeloid leukemia, acute basophilic leukemia} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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