engleski

Waist Circumference Correlates with Disease Severity in Acute Pancreatitis

Introduction: obesity is a well-known factor contributing to the etiology of acute pancreatitis (AP). Objectives: the aim of our study was to determine which obesity parameter correlates best with disease severity. Patients & Methods: in this retrospective study, medical histories of 156 patients with AP (81 men and 75 women, mean age 64, 2 ± 14, 5 years, average APACHE II score 8, 58 ± 4, 07) were analyzed. Body-mass index (BMI), waist circumference, hip circumference and waist- hip ratio were retrieved and their correlation with local, systemic complications and death outcomes were compared using receiver operating characteristic (ROC) curves. Results: among the researched parameters only waist circumference correlated with local, systemic complications and death outcomes. According to ROC curves, the cut- off value of 96 cm had 94.6% sensitivity and 40, 3% specificity value in predicting systemic complications (p = 0, 0018). The cut-off value of 103 cm had 68% sensitivity and 59, 4% specificity value in predicting local complications (p = 0, 0048), while the cut-off value of 100 cm predicted mortality with 80% sensitivity and 42, 5% specificity value (p = 0, 0031). Among other parameters, only waist-hip ratio – local complications ROC curve reached statistical significance ; for cut-off value of 0, 96, sensitivity was 80% and specificity 42, 5% (p = 0, 0101). Conclusion: statistical analysis has shown that in our case BMI was a poor parameter and waist circumference had a better correlation in predicting complications, including death, in patients with AP. However, low specificity is the problem which will impede waist circumference from gaining a more pronounced role in everyday practice.

Acute pancreatitis; Waist circumference; BMI

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