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Serial determination of magnesium and calcium in children with acute bronchoconstriction (CROSBI ID 573572)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Pavić, Ivan ; Dodig, Slavica ; Čepelak, Ivana ; Raos, Miljenko ; Zrinski Topić, Renata ; Živčić, Jadranka Serial determination of magnesium and calcium in children with acute bronchoconstriction // XXIXth Congress of the European Academy of Allergy and Clinical Immunology (EAACI ) "Asthma and rhinitis: mechanism of disease" : Abstract book. London : Delhi: Wiley-Blackwell, 2010. str. 722-722

Podaci o odgovornosti

Pavić, Ivan ; Dodig, Slavica ; Čepelak, Ivana ; Raos, Miljenko ; Zrinski Topić, Renata ; Živčić, Jadranka

engleski

Serial determination of magnesium and calcium in children with acute bronchoconstriction

Many metabolic functions of magnesium and calcium are tightly interrelated: magnesium acts on bronchial smooth muscle relaxation, and calcium act as a bronchoconstrictor. The aim of this study was to find out possible changes in serum concentration of magnesium and calcium, and in asthmatic children with moderate and severe bronchoconstriction, caused by respiratory syncytial virus infection. Thirty-two children with acute bronchoconstriction were included in the study. Inhalation of salbutamol was administered according to the severity of bronchoconstriction. Moderate bronchoconstriction was confirmed in 63% children, and severe bronchoconstriction in 37% children. Magnesium and calcium concentration, as well as magnesium/calcium ratio were determined on hospital admission and the third day of short-acting aˆ 2-adrenergic receptor agonist (salbutamol) administration. Therapy with salbutamol led to a relief of dyspnea within 36 h, and symptoms of viral infection have relieved. During follow-up period, magnesium was higher in children with moderate (but not in severe) bronchoconstriction than in healthy children, with consequently higher magnesium to calcium ratio. Also, correlation between magnesium and calcium concentration was confirmed. The present study demonstrated the concentration of magnesium, to undergo changes during salbutamol administration in children with moderate bronchoobstruction caused by respiratory syncytial virus infection.

magnesium; calcium; salbutamol; child; bronchoconstriction

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Podaci o prilogu

722-722.

2010.

objavljeno

Podaci o matičnoj publikaciji

XXIXth Congress of the European Academy of Allergy and Clinical Immunology (EAACI ) "Asthma and rhinitis: mechanism of disease" : Abstract book

London : Delhi: Wiley-Blackwell

Podaci o skupu

Congress of the European Academy of Allergy and Clinical Immunology (29 ; 2010)

poster

05.06.2010-09.06.2010

London, Ujedinjeno Kraljevstvo

Povezanost rada

Kliničke medicinske znanosti, Farmacija