engleski

The level of human cytokeratin 19 fragment as a biological pre-diagnostic signal in lung cancer

Lung cancer is world's leading cause of death. Since the lung parenchima is very low on nerve fibers, the symptoms often start in the advanced stage. Intermediate filaments are the diverse group of proteins that build up the eukaryotic cytoskeleton. Cytokeratin 19 is a acidic (type I) intermediate filament expressed in the startified and pseudostratified epithelia of the bronchial tree. Genetic changes that occur in lung cancer cause the increasd cell proliferation, ...

cytokeratin 19; lung cancer; diagnostics

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