engleski

Arterial stiffness indices in patients with chronic periodontitis

Background: Inflammatory periodontal disease is recognized as a risk factor for the development of atherosclerosis. The aim of this study was to assess the relationship between periodontal condition and arterial stiffness, compared to the periodontally healthy subjects. Methods: The study included 20 patients with chronic periodontitis (test group, 9 men and 11 women, mean age 57.5 ± 11.0 years) and 18 patients with healthy periodontium (control group, 7 men and 11 women, mean age 58.4 ± 8.2 years). Periodontal condition was assessed in terms of clinical attachment level with a periodontal probe. Arterial stiffness measurements on common carotid artery (CCA) were performed using Aloka ProSound ALPHA 10 with 13 MHz linear probe. Results: In comparison with the control group, test group showed statistically significant difference (p < 0.01) in the mean beta stiffness (11.06 ± 3.96), augmentation index (14.93 ± 11.36) and pulse wave velocity (7.48 ± 1.33), but only when measured on left CCA. Test group also showed statistically significant difference (p < 0.05) in the mean beta stiffness and pulse wave velocity when measured on the left and right CCA, respectively. No statistically significant differences were observed among groups regarding body mass index, blood pressure, pulse pressure and intima media thickness. Conclusions: Our results demonstrate that inflammatory periodontal disease can affect arterial haemodynamics, regardless alterations of intima media thickness. Further investigation with a larger patient sample is required in order to more accurately assess the arterial stiffness in patients with periodontitis.

Atherosclerotic plaque; IMT; periodontitis

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