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Pregled bibliografske jedinice broj: 512939

MAP Kinase Signaling Pathway : A Potential Biomarker of Environmental Pollution in the Mussel Mytilus galloprovincialis


Châtel, Amelie; Hamer, Bojan
MAP Kinase Signaling Pathway : A Potential Biomarker of Environmental Pollution in the Mussel Mytilus galloprovincialis // Mussels: Anatomy, Habitat and Environmental Impact / McGevin, Lauren E. (ur.).
New York: NOVA Publishers, 2011. str. 129-144


CROSBI ID: 512939 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
MAP Kinase Signaling Pathway : A Potential Biomarker of Environmental Pollution in the Mussel Mytilus galloprovincialis

Autori
Châtel, Amelie ; Hamer, Bojan

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Mussels: Anatomy, Habitat and Environmental Impact

Urednik/ci
McGevin, Lauren E.

Izdavač
NOVA Publishers

Grad
New York

Godina
2011

Raspon stranica
129-144

ISBN
978-1-61761-763-8

Ključne riječi
MAPKs, p38, JNK and ERK

Sažetak
In the present study, the effects of environmental pollutants have been investigated in the Mediterranean mussel Mytilus galloprovincialis as sentinel species. For the purpose of detecting water contamination in the early stages, biomarkers of effect and exposure must be studied. Most specifically, proteins of intracellular signaling pathways appear to be very interesting targets as their conservation through evolution is maintained and since their modulation via environmental relevant levels of chemical contaminants is an indicating sign of stress for bivalves. Genes encoding the Mitogen-Activated Protein Kinases (MAPKs) in M. galloprovicialis confirmed high homology with those of other vertebrates and invertebrates. Further, mussels were exposed to various model agents: tributyltin, hydrogen peroxide and water soluble fraction of diesel fuel and the activation/phosphorylation of the MAPKs p38, JNK and ERK were evaluated by a new developed ELISA assay.

Izvorni jezik
Engleski

Znanstvena područja
Geologija, Biologija



POVEZANOST RADA


Projekt / tema
098-0982705-2724 - Učinak zagađenja na programirane biosinteze morskih beskralješnjaka (Batel, Renato, MZOS - )

Ustanove
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Bojan Hamer (autor)

Citiraj ovu publikaciju

Châtel, Amelie; Hamer, Bojan
MAP Kinase Signaling Pathway : A Potential Biomarker of Environmental Pollution in the Mussel Mytilus galloprovincialis // Mussels: Anatomy, Habitat and Environmental Impact / McGevin, Lauren E. (ur.).
New York: NOVA Publishers, 2011. str. 129-144
Châtel, A. & Hamer, B. (2011) MAP Kinase Signaling Pathway : A Potential Biomarker of Environmental Pollution in the Mussel Mytilus galloprovincialis. U: McGevin, L. (ur.) Mussels: Anatomy, Habitat and Environmental Impact. New York, NOVA Publishers, str. 129-144.
@inbook{inbook, editor = {McGevin, L.}, year = {2011}, pages = {129-144}, keywords = {MAPKs, p38, JNK and ERK}, isbn = {978-1-61761-763-8}, title = {MAP Kinase Signaling Pathway : A Potential Biomarker of Environmental Pollution in the Mussel Mytilus galloprovincialis}, keyword = {MAPKs, p38, JNK and ERK}, publisher = {NOVA Publishers}, publisherplace = {New York} }




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