engleski

The first ferrocene analogues of muramyldipeptide

The two structurally interesting bioorganometallic analogues of muramyldipeptide (MDP) with potential immunomodulatory activity were synthesized starting from the O-protected N-acetylmuramic acid (MurNAc), L- or D-Ala and 1'-aminoferrocene-1-carboxylic acid (Fca). They were fully characterized by IR, 1H NMR, 13C NMR and CD spectroscopy as well as by FD mass spectrometry.

ferrocene ; 1'-fminoferrocene-1-carboxylic acid (Fca) ; muramyldipeptide (MDP) ; beta-Turn ; intramolecular hydrogen bond (IHB)

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