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Pregled bibliografske jedinice broj: 505894

Health-related quality of life and fatigue in patients with adrenal incidentaloma


Kaštelan, Darko; Džubur, Feđa; Dušek, Tina; Poljičanin, Tamara; Crnčević Orlić, Željka; Kraljević, Ivana; Solak, Mirsala; Benčević, Tanja; Aganović, Izet; Knežević, Nikola et al.
Health-related quality of life and fatigue in patients with adrenal incidentaloma // Endocrine (Basingstoke), 40 (2011), 1; 84-89 doi:10.1007/s12020-011-9456-3 (međunarodna recenzija, članak, znanstveni)


Naslov
Health-related quality of life and fatigue in patients with adrenal incidentaloma

Autori
Kaštelan, Darko ; Džubur, Feđa ; Dušek, Tina ; Poljičanin, Tamara ; Crnčević Orlić, Željka ; Kraljević, Ivana ; Solak, Mirsala ; Benčević, Tanja ; Aganović, Izet ; Knežević, Nikola ; Kaštelan, Željko ; Koršić, Mirko

Izvornik
Endocrine (Basingstoke) (1355-008X) 40 (2011), 1; 84-89

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
adrenal incidentaloma ; quality of life ; subclinical Cushing's syndrome ; EQ-5D ; SF-36 ; MFI-20

Sažetak
The objective of the present study was to examine several dimensions of quality of life (QoL) and fatigue in patients with adrenal incidentaloma. This was a case-control study designed to analyze patient outcomes using three validated generic QoL questionnaires, EQ-5D, SF-36 and MFI-20, the results of which were compared to those obtained for age- and sex-matched controls. The study population comprised 139 consecutive patients with nonfunctioning adrenal masses (104 females, 35 males ; age 59.1±10.8) and 139 age- and sex-matched controls. Results: Reduced QoL was found in patients with adrenal incidentaloma as compared to controls. Dimensions of QoL that were notably affected included mobility (p=0.03), performance of usual activities (p=0.002) and anxiety/depression (p=0.04) as evaluated using the EQ-5D ; physical functioning (p<0.001), physical role (p<0.001), general health (p<0.001), vitality (p=0.001), social functioning (p=0.001) and emotional role (p<0.001) as evaluated using the SF-36 ; and physical fatigue (p=0.04) as assessed using the MFI-20 questionnaire. In addition, perceived health on a visual analogue scale was also significantly lower in patients than in controls (64.8±19.2 vs. 77.1±15.1 ; p<0.001). Patients with adrenal incidentaloma reported reduced QoL and a higher level of physical fatigue compared to age- and sex-matched controls. This subject will benefit from further studies comparing QoL outcomes of laparoscopic adrenalectomy vs. no treatment in patients with adrenal incidentaloma.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
062-0620226-0208 - Kost kao ciljni organ u šećernoj bolesti i upalnim bolestima crijeva (Željka Crnčević Orlić, )
108-0000000-3496 - Incidentalomi nadbubrežne žlijezde kao uzrok metaboličkog sindroma (Darko Kaštelan, )

Ustanove
Klinika za dijabetes, endokrinologiju i bolesti metabolizma Vuk Vrhovac,
Medicinski fakultet, Zagreb,
KBC Split,
Klinika za plućne bolesti "Jordanovac",
Klinički bolnički centar Rijeka

Citiraj ovu publikaciju

Kaštelan, Darko; Džubur, Feđa; Dušek, Tina; Poljičanin, Tamara; Crnčević Orlić, Željka; Kraljević, Ivana; Solak, Mirsala; Benčević, Tanja; Aganović, Izet; Knežević, Nikola et al.
Health-related quality of life and fatigue in patients with adrenal incidentaloma // Endocrine (Basingstoke), 40 (2011), 1; 84-89 doi:10.1007/s12020-011-9456-3 (međunarodna recenzija, članak, znanstveni)
Kaštelan, D., Džubur, F., Dušek, T., Poljičanin, T., Crnčević Orlić, Ž., Kraljević, I., Solak, M., Benčević, T., Aganović, I. & Knežević, N. (2011) Health-related quality of life and fatigue in patients with adrenal incidentaloma. Endocrine (Basingstoke), 40 (1), 84-89 doi:10.1007/s12020-011-9456-3.
@article{article, year = {2011}, pages = {84-89}, DOI = {10.1007/s12020-011-9456-3}, keywords = {adrenal incidentaloma, quality of life, subclinical Cushing's syndrome, EQ-5D, SF-36, MFI-20}, journal = {Endocrine (Basingstoke)}, doi = {10.1007/s12020-011-9456-3}, volume = {40}, number = {1}, issn = {1355-008X}, title = {Health-related quality of life and fatigue in patients with adrenal incidentaloma}, keyword = {adrenal incidentaloma, quality of life, subclinical Cushing's syndrome, EQ-5D, SF-36, MFI-20} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • MEDLINE


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