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Pregled bibliografske jedinice broj: 505008

Synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins, and their conjugation to monoclonal antibodies for use in photodynamic therapy


Peša, Nela; Smith, Karen A.; Savoie, Huguette; Greenman, John; Boyle, Ross W.
Synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins, and their conjugation to monoclonal antibodies for use in photodynamic therapy // Tetrapyrrole Discussion Group Meeting (TPDG Meetings)
Hull, Velika Britanija, 2005. (poster, međunarodna recenzija, neobjavljeni rad, znanstveni)


CROSBI ID: 505008 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins, and their conjugation to monoclonal antibodies for use in photodynamic therapy

Autori
Peša, Nela ; Smith, Karen A. ; Savoie, Huguette ; Greenman, John ; Boyle, Ross W.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
Tetrapyrrole Discussion Group Meeting (TPDG Meetings)

Mjesto i datum
Hull, Velika Britanija, 30.06-01.07.2005

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Porphyrin synthesis; Monoclonal antibody; Bioconjugation; Photodynamic therapy

Sažetak
Successful synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins are described. The potential of these compounds as targeted photosensitisers for use in photodynamic therapy(PDT) is demonstrated by their efficient conjugation to monoclonal antibodies and the ability of the bioconjugates to bind and photodynamically inactivate cancer cells that express the corresponding antigen.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Ustanove:
Sveučilište u Osijeku - Odjel za kemiju

Profili:

Avatar Url Nela Malatesti (autor)


Citiraj ovu publikaciju:

Peša, Nela; Smith, Karen A.; Savoie, Huguette; Greenman, John; Boyle, Ross W.
Synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins, and their conjugation to monoclonal antibodies for use in photodynamic therapy // Tetrapyrrole Discussion Group Meeting (TPDG Meetings)
Hull, Velika Britanija, 2005. (poster, međunarodna recenzija, neobjavljeni rad, znanstveni)
Peša, N., Smith, K., Savoie, H., Greenman, J. & Boyle, R. (2005) Synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins, and their conjugation to monoclonal antibodies for use in photodynamic therapy. U: Tetrapyrrole Discussion Group Meeting (TPDG Meetings).
@article{article, year = {2005}, keywords = {Porphyrin synthesis, Monoclonal antibody, Bioconjugation, Photodynamic therapy}, title = {Synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins, and their conjugation to monoclonal antibodies for use in photodynamic therapy}, keyword = {Porphyrin synthesis, Monoclonal antibody, Bioconjugation, Photodynamic therapy}, publisherplace = {Hull, Velika Britanija} }
@article{article, year = {2005}, keywords = {Porphyrin synthesis, Monoclonal antibody, Bioconjugation, Photodynamic therapy}, title = {Synthetic routes to cationic isothiocyanato diphenyl and tetraphenyl porphyrins, and their conjugation to monoclonal antibodies for use in photodynamic therapy}, keyword = {Porphyrin synthesis, Monoclonal antibody, Bioconjugation, Photodynamic therapy}, publisherplace = {Hull, Velika Britanija} }




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