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Pregled bibliografske jedinice broj: 504717

Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer


Smith, Karen A.; Madden, Leigh A.; Hudson, Robert; Pesa, Nela; Swann, Joanne; Savoie, Huguette; Boyle, Ross W.; Greenman, John
Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer // International Journal of Molecular Medicine / Spandidos, Demetrios A. (ur.).
Atena, Grčka: Spandidos Publications Ltd., 2003. str. S64-S64 (poster, međunarodna recenzija, sažetak, znanstveni)


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Naslov
Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer

Autori
Smith, Karen A. ; Madden, Leigh A. ; Hudson, Robert ; Pesa, Nela ; Swann, Joanne ; Savoie, Huguette ; Boyle, Ross W. ; Greenman, John

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
International Journal of Molecular Medicine / Spandidos, Demetrios A. - Atena, Grčka : Spandidos Publications Ltd., 2003, S64-S64

Skup
8th World Congress on Advances in Oncology and 6th International Symposium on Molecular Medicine

Mjesto i datum
Kreta, Grčka, 16-18.10.2003

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Bioconjugation; Porphyrin; Monoclonal antibody; Photodynamic therapy; Cancer

Sažetak
The synthesis of several three cationic 5, 15-diphenyl porphyrins, bearing an isothiocyanate group for conjugation to proteins is described. The potential of these compounds as targeted photosensitisers for use in photodynamic therapy (PDT) is demonstrated by their efficient conjugation to monoclonal antibodies and the ability of the bioconjugates to bind cancer cells that express the corresponding antigen.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Ustanove:
Sveučilište u Osijeku - Odjel za kemiju

Profili:

Avatar Url Nela Malatesti (autor)


Citiraj ovu publikaciju:

Smith, Karen A.; Madden, Leigh A.; Hudson, Robert; Pesa, Nela; Swann, Joanne; Savoie, Huguette; Boyle, Ross W.; Greenman, John
Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer // International Journal of Molecular Medicine / Spandidos, Demetrios A. (ur.).
Atena, Grčka: Spandidos Publications Ltd., 2003. str. S64-S64 (poster, međunarodna recenzija, sažetak, znanstveni)
Smith, K., Madden, L., Hudson, R., Pesa, N., Swann, J., Savoie, H., Boyle, R. & Greenman, J. (2003) Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer. U: Spandidos, D. (ur.)International Journal of Molecular Medicine.
@article{article, editor = {Spandidos, D.}, year = {2003}, pages = {S64-S64}, keywords = {Bioconjugation, Porphyrin, Monoclonal antibody, Photodynamic therapy, Cancer}, title = {Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer}, keyword = {Bioconjugation, Porphyrin, Monoclonal antibody, Photodynamic therapy, Cancer}, publisher = {Spandidos Publications Ltd.}, publisherplace = {Kreta, Gr\v{c}ka} }
@article{article, editor = {Spandidos, D.}, year = {2003}, pages = {S64-S64}, keywords = {Bioconjugation, Porphyrin, Monoclonal antibody, Photodynamic therapy, Cancer}, title = {Characterisation of novel porphyrin-antibody conjugates for use in photodynamic therapy of cancer}, keyword = {Bioconjugation, Porphyrin, Monoclonal antibody, Photodynamic therapy, Cancer}, publisher = {Spandidos Publications Ltd.}, publisherplace = {Kreta, Gr\v{c}ka} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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