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Pregled bibliografske jedinice broj: 503008

Assessment of cytogenetic damage and oxidative stress in personnel occupationally exposed to the pulsed microwave radiation of marine radar equipment


Garaj-Vrhovac, Vera; Gajski, Goran; Pažanin, Senijo; Šarolić, Antonio; Domijan, Ana-Marija; Flajs, Dubravka; Peraica, Maja
Assessment of cytogenetic damage and oxidative stress in personnel occupationally exposed to the pulsed microwave radiation of marine radar equipment // International journal of hygiene and environmental health, 214 (2011), 1; 59-65 doi:10.1016/j.ijheh.2010.08.003 (međunarodna recenzija, članak, znanstveni)


Naslov
Assessment of cytogenetic damage and oxidative stress in personnel occupationally exposed to the pulsed microwave radiation of marine radar equipment

Autori
Garaj-Vrhovac, Vera ; Gajski, Goran ; Pažanin, Senijo ; Šarolić, Antonio ; Domijan, Ana-Marija ; Flajs, Dubravka ; Peraica, Maja

Izvornik
International journal of hygiene and environmental health (1438-4639) 214 (2011), 1; 59-65

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Pulsed microwave radiation; occupational exposure; peripheral blood lymphocytes; DNA damage; oxidative stress

Sažetak
Due to increased usage of microwave radiation, there are concerns of its adverse effect in today's society. Keeping this in view, study was aimed at workers occupationally exposed to pulsed microwave radiation, originating from marine radars. Electromagnetic field strength was measured at assigned marine radar frequencies (3GHz, 5.5GHz and 9.4GHz) and corresponding specific absorption rate values were determined. Parameters of the comet assay and micronucleus test were studied both in the exposed workers and in corresponding unexposed subjects. Differences between mean tail intensity (0.67 vs. 1.22) and moment (0.08 vs. 0.16) as comet assay parameters and micronucleus test parameters (micronuclei, nucleoplasmic bridges and nuclear buds) were statistically significant between the two examined groups, suggesting that cytogenetic alterations occurred after microwave exposure. Concentrations of glutathione and malondialdehyde were measured spectrophotometrically and using high performance liquid chromatography. The glutathione concentration in exposed group was significantly lower than in controls (1.24 vs. 0.53) whereas the concentration of malondialdehyde was significantly higher (1.74 vs. 3.17), indicating oxidative stress. Results suggests that pulsed microwaves from working environment can be the cause of genetic and cell alterations and that oxidative stress can be one of the possible mechanisms of DNA and cell damage.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
022-0222148-2125 - Mutageni i antimutageni u ekogenetičkim istraživanjima (Vera Garaj-Vrhovac, )
022-0222148-2142 - Toksični učinci mikotoksina na ljude i životinje (Maja Peraica, )
023-0000000-3273 - Mjerenja u području EMC i istraživanja EM utjecaja na zdravlje (Antonio Šarolić, )

Ustanove
Institut za medicinska istraživanja i medicinu rada, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Scopus


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