Cerebral Hemodynamics In Patients With Type II Of Diabetes Mellitus And Assessment Of Transcranial Dopler (CROSBI ID 568562)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Bitunjac, Milan ; Dikanović, Marinko ; Lojen, Gordana ; Ažman, Dražen ; Šapina, Lidija ; Kadojić, Dragutin
engleski
Cerebral Hemodynamics In Patients With Type II Of Diabetes Mellitus And Assessment Of Transcranial Dopler
Background: Diabetics have a 3-fold risk for cardiovascular diseases compared with non- diabetics. This study was designed to evaluate cerebral hemodynamic changes related to type 2 diabetes mellitus (DM) with transcranial Doppler ultrasonography (TCD). TCD is a highly sensitive and specific method of quick bedside assessment of cerebrovascular circulation hemodynamics. Patients and Methods: In a prospective study, we compared a group of 100 patients with the diagnosis of type 2 diabetes mellitus (aged 48 to 67 years) and an age- and sex-matched control group of 100 healthy subjects without diabetes mellitus. We measured flow velocities (Vm) and the Gosling pulsatility index (PI) of the middle cerebral artery (MCA). Results: The rate of TCD abnormalities was significantly higher in diabetic patients than in healthy control subjects (55% vs. 11%, P<0.05). The PI was significantly higher in diabetic patients than in healthy controls (P<0.001). Atherosclerotic changes were found in 34.0% and 71.4% of patients suffering from diabetes for <5 and ≥ 5 years, respectively. Conclusion: This study suggests that TCD is a useful marker for the detection of diabetic cerebrovascular changes. The duration and type of diabetes were found to have an impact on the development of pathologic cerebrovascular changes.
Cerebral Hemodynamics ; Type II Diabetes Mellitus ; Transcranial Dopler
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Podaci o prilogu
25-25.
2010.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
42nd Danube Symposium for Neurological Science and Continuing Education
poster
21.10.2010-23.10.2010
Zagreb, Hrvatska