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Pregled bibliografske jedinice broj: 490849

New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery


Hearnden, Vanessa; Sankar, Vidya; Hull, Katrusha; Vidović Juras, Danica; Greenberg, Martin; Kerr, Ross A.; Lockhart, Peter B.; Patton, Lauren L.; Porter, Stephen; Thornhill, Martin
New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery // Advanced drugs delivery reviews, 64 (2012), 1; 16-28 doi:10.1016/j.addr.2011.02.008 (recenziran, pregledni rad, stručni)


Naslov
New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery

Autori
Hearnden, Vanessa ; Sankar, Vidya ; Hull, Katrusha ; Vidović Juras, Danica ; Greenberg, Martin ; Kerr, Ross A. ; Lockhart, Peter B. ; Patton, Lauren L. ; Porter, Stephen ; Thornhill, Martin

Izvornik
Advanced drugs delivery reviews (0169-409X) 64 (2012), 1; 16-28

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
oral mucosa; drug delivery technology; trans-mucosal; local drug delivery; systemic drug delivery; formulations; targeting; mucoadhesives; polymersomes

Sažetak
The oral mucosa's accessibility, excellent blood supply, by-pass of hepatic first-pass metabolism, rapid repair and permeability profile make it an attractive site for local and systemic drug delivery. Technological advances in mucoadhesives, sustained drug release, permeability enhancers and drug delivery vectors are increasing the efficient delivery of drugs to treat oral and systemic diseases. When treating oral diseases, these advances result in enhanced therapeutic efficacy, reduced drug wastage and the prospect of using biological agents such as genes, peptides and antibodies. These technologies are also increasing the repertoire of drugs that can be delivered across the oral mucosa to treat systemic diseases. Trans-mucosal delivery is now a favoured route for non-parenteral administration of emergency drugs and drugs where a rapid onset of action is required. Furthermore, advances in drug delivery technology are bringing closer the possibility of transmucosal systemic delivery of biological agents.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina, Farmacija



POVEZANOST RADA


Projekt / tema
065-0650445-0485 - Salivarni markeri oralnih bolesti i njihova primjena (Vanja Vučićević Boras, )

Ustanove
Stomatološki fakultet, Zagreb,
Klinički bolnički centar Zagreb

Profili:

Avatar Url Danica Vidović Juras (autor)

Citiraj ovu publikaciju

Hearnden, Vanessa; Sankar, Vidya; Hull, Katrusha; Vidović Juras, Danica; Greenberg, Martin; Kerr, Ross A.; Lockhart, Peter B.; Patton, Lauren L.; Porter, Stephen; Thornhill, Martin
New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery // Advanced drugs delivery reviews, 64 (2012), 1; 16-28 doi:10.1016/j.addr.2011.02.008 (recenziran, pregledni rad, stručni)
Hearnden, V., Sankar, V., Hull, K., Vidović Juras, D., Greenberg, M., Kerr, R., Lockhart, P., Patton, L., Porter, S. & Thornhill, M. (2012) New Developments & Opportunities in Local and Systemic Oral Mucosal Drug Delivery. Advanced drugs delivery reviews, 64 (1), 16-28 doi:10.1016/j.addr.2011.02.008.
@article{article, year = {2012}, pages = {16-28}, DOI = {10.1016/j.addr.2011.02.008}, keywords = {oral mucosa, drug delivery technology, trans-mucosal, local drug delivery, systemic drug delivery, formulations, targeting, mucoadhesives, polymersomes}, journal = {Advanced drugs delivery reviews}, doi = {10.1016/j.addr.2011.02.008}, volume = {64}, number = {1}, issn = {0169-409X}, title = {New Developments and Opportunities in Local and Systemic Oral Mucosal Drug Delivery}, keyword = {oral mucosa, drug delivery technology, trans-mucosal, local drug delivery, systemic drug delivery, formulations, targeting, mucoadhesives, polymersomes} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • BIOSIS Previews (Biological Abstracts)
  • Chemical Engineering and Biotechnology Abstracts
  • EMBASE (Excerpta Medica)
  • International Pharmaceutical Abstracts (IPA)
  • MEDLINE
  • BIOBASE, Scopus


Citati