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Pregled bibliografske jedinice broj: 488309

Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8% gel and Utrogestan capsules, used for luteal support


Šimunić, Velimir; Tomić, Vlatka; Tomić, Jozo; Nizić, Dinko.
Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8% gel and Utrogestan capsules, used for luteal support // Fertility and sterility, 87 (2007), 1; 83-87 doi:10.1016/j.fertnstert.2006.05.067 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 488309 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8% gel and Utrogestan capsules, used for luteal support

Autori
Šimunić, Velimir ; Tomić, Vlatka ; Tomić, Jozo ; Nizić, Dinko.

Izvornik
Fertility and sterility (0015-0282) 87 (2007), 1; 83-87

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
luteal phase support; vaginal progesterone; efficiency; tolerability; pregnancy rate

Sažetak
Objective was to compare the efficacy and tolerability of two different types of vaginal progesterone (P), Crinone 8% gel (Fleet Laboratories Ltd., Watford, United Kingdom) and Utrogestan capsules (Laboratories Besins International, Paris, France), used for luteal support after in vitro fertilization (IVF) cycles. Design: Cohort study. In Vitro Fertilization Polyclinic, Zagreb, Croatia. A total of 285 women aged < or =37 years undergoing IVF-embryo transfer treatment. Patients were treated with either Crinone 8% vaginal P gel (90 mg) administered daily, or Utrogestan vaginal capsules (2 x 100 mg) administered three times daily. Progesterone was administered from the day of oocyte retrieval (day 0) to menses or, in a case of pregnancy, until week 12. Clinical pregnancy rate. The tolerability and acceptability of both preparations were determined by a questionnaire given to patients. The similar rates of clinical pregnancies (33.1% vs. 30.9%) [corrected] were obtained by using either Crinone 8% vaginal P gel or Utrogestan vaginal capsules. Overall tolerability and acceptability were significantly better in the Crinone group than in the Utrogestan group. The efficacy of the two vaginal P formulations was nearly the same, but the tolerability and acceptability of Crinone 8% gel were superior, in the opinion of patients.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Klinički bolnički centar Zagreb

Profili:

Avatar Url Vlatka Tomić (autor)

Avatar Url Velimir Šimunić (autor)

Citiraj ovu publikaciju

Šimunić, Velimir; Tomić, Vlatka; Tomić, Jozo; Nizić, Dinko.
Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8% gel and Utrogestan capsules, used for luteal support // Fertility and sterility, 87 (2007), 1; 83-87 doi:10.1016/j.fertnstert.2006.05.067 (međunarodna recenzija, članak, znanstveni)
Šimunić, V., Tomić, V., Tomić, J. & Nizić, D. (2007) Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8% gel and Utrogestan capsules, used for luteal support. Fertility and sterility, 87 (1), 83-87 doi:10.1016/j.fertnstert.2006.05.067.
@article{article, year = {2007}, pages = {83-87}, DOI = {10.1016/j.fertnstert.2006.05.067}, keywords = {luteal phase support, vaginal progesterone, efficiency, tolerability, pregnancy rate}, journal = {Fertility and sterility}, doi = {10.1016/j.fertnstert.2006.05.067}, volume = {87}, number = {1}, issn = {0015-0282}, title = {Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8\% gel and Utrogestan capsules, used for luteal support}, keyword = {luteal phase support, vaginal progesterone, efficiency, tolerability, pregnancy rate} }
@article{article, year = {2007}, pages = {83-87}, DOI = {10.1016/j.fertnstert.2006.05.067}, keywords = {luteal phase support, vaginal progesterone, efficiency, tolerability, pregnancy rate}, journal = {Fertility and sterility}, doi = {10.1016/j.fertnstert.2006.05.067}, volume = {87}, number = {1}, issn = {0015-0282}, title = {Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8\% gel and Utrogestan capsules, used for luteal support}, keyword = {luteal phase support, vaginal progesterone, efficiency, tolerability, pregnancy rate} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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