Recent Achievements in Simulated Moving Bed (SMB) Technology. Part I (CROSBI ID 166545)
Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija
Podaci o odgovornosti
Šunjić, Vitomir ; Franić, Dean ; Kontrec, Darko ; Roje, Marin
engleski
Recent Achievements in Simulated Moving Bed (SMB) Technology. Part I
Simulated moving bed (SMB) technology is over half a century known in continuous chromatographic separation of binary mixtures. Invented and developed in the petrochemical and sugar industries, it was recognized by organic chemists in the pharmaceutical industry as a powerful tool in separation of racemic mixtures. Over the years, it was developed into a standard laboratory, then pilot-plant and finally large-scale method for production of chiral compounds in the optically pure form. Final products of this technology are enantiopure drugs, other biologically active compounds and their intermediates. In Part I of this review, the basic principles and selected examples of recent SMB technology applications are presented.
Simulated moving bed ; continuous chromatography ; triangle theory ; enantioseparation
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Podaci o izdanju
59 (6)
2010.
283-294
objavljeno
0022-9830
1334-9090
Povezanost rada
Kemija