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Recent Achievements in Simulated Moving Bed (SMB) Technology. Part I


Šunjić, Vitomir; Franić, Dean; Kontrec, Darko; Roje, Marin
Recent Achievements in Simulated Moving Bed (SMB) Technology. Part I // Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 59 (2010), 6; 283-294 (međunarodna recenzija, pregledni rad, znanstveni)


Naslov
Recent Achievements in Simulated Moving Bed (SMB) Technology. Part I

Autori
Šunjić, Vitomir ; Franić, Dean ; Kontrec, Darko ; Roje, Marin

Izvornik
Kemija u industriji : časopis kemičara i tehnologa Hrvatske (0022-9830) 59 (2010), 6; 283-294

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Simulated moving bed ; continuous chromatography ; triangle theory ; enantioseparation

Sažetak
Simulated moving bed (SMB) technology is over half a century known in continuous chromatographic separation of binary mixtures. Invented and developed in the petrochemical and sugar industries, it was recognized by organic chemists in the pharmaceutical industry as a powerful tool in separation of racemic mixtures. Over the years, it was developed into a standard laboratory, then pilot-plant and finally large-scale method for production of chiral compounds in the optically pure form. Final products of this technology are enantiopure drugs, other biologically active compounds and their intermediates. In Part I of this review, the basic principles and selected examples of recent SMB technology applications are presented.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
098-0982904-2910 - Kiralni organski materijali – sintetska, strukturna i funkcionalna istraživanja (Vladimir Vinković, )
098-0982933-2908 - Kiralni građevni blokovi za biološki aktivne molekule. Sinteza i reaktivnost (Zdenko Hameršak, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)
  • Scopus