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Common Acute Lymphoblastic Leukemia Ph+ following Langerhans Cell Histiocytosis in a Multi-Malformed Chils with INV (9) (p12 ; q13) (mat): Case report


Pavelić, Jasminka; Čulić, Srđana; Čulić, Vida
Common Acute Lymphoblastic Leukemia Ph+ following Langerhans Cell Histiocytosis in a Multi-Malformed Chils with INV (9) (p12 ; q13) (mat): Case report // Acta medica Okayama, 64 (2010), 4; 263-265 doi:10.18926/AMO/40135 (međunarodna recenzija, članak, znanstveni)


Naslov
Common Acute Lymphoblastic Leukemia Ph+ following Langerhans Cell Histiocytosis in a Multi-Malformed Chils with INV (9) (p12 ; q13) (mat): Case report

Autori
Pavelić, Jasminka ; Čulić, Srđana ; Čulić, Vida

Izvornik
Acta medica Okayama (0386-300X) 64 (2010), 4; 263-265

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Acute lymphoblastic leukemia ; genetic changes ; langerhans cell histiocytosis

Sažetak
The occurrence of Langerhans cell histiocytosis (LCH) and another malignancy in the same patient is infrequent but has been recognized. The genetic changes that could be responsible for LCH and/or concomitant leukemia development are obscure. To the best of our knowledge, this is the first description of constitutional maternally derived inv (9) (p12 ; q13) in an LCH patient, and also of the development of common ALL Ph after LCH diagnosis and therapy. The potential significance of these findings [inv (9)LCHALL Ph] and their mutual relationship are unknown. Therefore, cooperative studies of large numbers of patients are needed to identify the common risk factors, if any.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
098-0982464-2394 - Gensko liječenje tumora djelovanjem na molekule imunološkog sustava (Jasminka Pavelić, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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