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Pregled bibliografske jedinice broj: 47743

Metal exposure studies: role of toxicology and epidemiology in public health policy


Šarić, Marko; Piasek, Martina
Metal exposure studies: role of toxicology and epidemiology in public health policy // Arhiv za higijenu rada i toksikologiju = Archives of Industrial Hygiene and Toxicology, 48 (1997), 3; 307-317 (podatak o recenziji nije dostupan, priopćenje (short communication), znanstveni)


CROSBI ID: 47743 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Metal exposure studies: role of toxicology and epidemiology in public health policy

Autori
Šarić, Marko ; Piasek, Martina

Izvornik
Arhiv za higijenu rada i toksikologiju = Archives of Industrial Hygiene and Toxicology (0004-1254) 48 (1997), 3; 307-317

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, priopćenje (short communication), znanstveni

Ključne riječi
cytotoxic effects; lead exposure; manganese exposure; reproductive effects; respiratory effects

Sažetak
Following the idea of interrelated role of epidemiology and toxicology in risk assessment and dose response evaluation, this paper presents certain experiences from the authors' studies of health effects of environmental exposure to lead and manganese. Epidemiologic observations of adverse effects on female reproductive integrity in a lead smeltery area agree with the experimental data. Animal studies show that the adverse reproductive effects in females are time and dose-related, and reversible after exposure has ceased. Field studies show that effects of manganese on the respiratory system in a polluted region are dose, age and season-related. Cytotoxic effects of manganese, including the inhibitory effect on alveolar macrophages described in in vitro studies on mammalian cells confirm the epidemiologic observations. Authors conclude that in the process of risk assessment, toxicology and epidemiology have to act together. Available human data should be combined with experimental findings and data on the mechanism of toxic action.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita



POVEZANOST RADA


Projekti:
00220102

Ustanove:
Institut za medicinska istraživanja i medicinu rada, Zagreb

Profili:

Avatar Url Marko Šarić (autor)

Avatar Url Martina Piasek (autor)


Citiraj ovu publikaciju

Šarić, Marko; Piasek, Martina
Metal exposure studies: role of toxicology and epidemiology in public health policy // Arhiv za higijenu rada i toksikologiju = Archives of Industrial Hygiene and Toxicology, 48 (1997), 3; 307-317 (podatak o recenziji nije dostupan, priopćenje (short communication), znanstveni)
Šarić, M. & Piasek, M. (1997) Metal exposure studies: role of toxicology and epidemiology in public health policy. Arhiv za higijenu rada i toksikologiju = Archives of Industrial Hygiene and Toxicology, 48 (3), 307-317.
@article{article, year = {1997}, pages = {307-317}, keywords = {cytotoxic effects, lead exposure, manganese exposure, reproductive effects, respiratory effects}, journal = {Arhiv za higijenu rada i toksikologiju = Archives of Industrial Hygiene and Toxicology}, volume = {48}, number = {3}, issn = {0004-1254}, title = {Metal exposure studies: role of toxicology and epidemiology in public health policy}, keyword = {cytotoxic effects, lead exposure, manganese exposure, reproductive effects, respiratory effects} }
@article{article, year = {1997}, pages = {307-317}, keywords = {cytotoxic effects, lead exposure, manganese exposure, reproductive effects, respiratory effects}, journal = {Arhiv za higijenu rada i toksikologiju = Archives of Industrial Hygiene and Toxicology}, volume = {48}, number = {3}, issn = {0004-1254}, title = {Metal exposure studies: role of toxicology and epidemiology in public health policy}, keyword = {cytotoxic effects, lead exposure, manganese exposure, reproductive effects, respiratory effects} }

Časopis indeksira:


  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka:


  • Biological Abstracts
  • Chemical Abstracts
  • Excerpta Medica
  • Index Medicus
  • Industrial Hygiene Digest
  • MEDLINE
  • TOXLINE





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