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Pregled bibliografske jedinice broj: 475978

Expression of MAGE-1, -2 and -3 genes in primary and metastatic lesions of human malignant melanomas


Juretić, Antonio; Knežević, Fabijan; Spagnoli, G.C.; Jürgens-Göbel, J.; Šamija, Mirko; Herceg, Tonko; Šeparović, Viktor; Eljuga, Damir.; Turić, Marko; Heberer, M.
Expression of MAGE-1, -2 and -3 genes in primary and metastatic lesions of human malignant melanomas // Croatian Medical Journal, 37 (1996), 2; 119-122 (međunarodna recenzija, članak, znanstveni)


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Naslov
Expression of MAGE-1, -2 and -3 genes in primary and metastatic lesions of human malignant melanomas

Autori
Juretić, Antonio ; Knežević, Fabijan ; Spagnoli, G.C. ; Jürgens-Göbel, J. ; Šamija, Mirko ; Herceg, Tonko ; Šeparović, Viktor ; Eljuga, Damir. ; Turić, Marko ; Heberer, M.

Izvornik
Croatian Medical Journal (0353-9504) 37 (1996), 2; 119-122

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
MAGE-1; -2 and -3 genes; human malignant melanomas

Sažetak
Analysis of the expression of MAGE-1, -2 and -3 genes in melanoma tissue samples. MAGE-1, - 2 and -3 genes encode human melanoma antigens recognized by syngeneic cytotoxic lymphocytes. A reverse transcription-polymerase chain reaction (RT-PCR) was used to analyze the expression of MAGE-1, -2 and -3 genes in 15 melanoma samples at various stages of progress. The highest occurrence of gene expression was found in MAGE-1 (8/15, 53%), while MAGE-2 was expressed in 3 (20%), and MAGE-3 in 4 tumors (27%). In two samples, concomitant expression of MAGE-1 and MAGE-3 were found. Concomitant expressions of MAGE-1 and MAGE-3 genes on the one hand, and of MAGE-2 and MAGE-3 genes on the other, were observed in only one case each. Our results on MAGE-1 gene expression are similar to those found in previous research, whereas the frequencies of MAGE-2 and MAGE-3 genes are lower than the published data.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinika za tumore

Citiraj ovu publikaciju

Juretić, Antonio; Knežević, Fabijan; Spagnoli, G.C.; Jürgens-Göbel, J.; Šamija, Mirko; Herceg, Tonko; Šeparović, Viktor; Eljuga, Damir.; Turić, Marko; Heberer, M.
Expression of MAGE-1, -2 and -3 genes in primary and metastatic lesions of human malignant melanomas // Croatian Medical Journal, 37 (1996), 2; 119-122 (međunarodna recenzija, članak, znanstveni)
Juretić, A., Knežević, F., Spagnoli, G., Jürgens-Göbel, J., Šamija, M., Herceg, T., Šeparović, V., Eljuga, D., Turić, M. & Heberer, M. (1996) Expression of MAGE-1, -2 and -3 genes in primary and metastatic lesions of human malignant melanomas. Croatian Medical Journal, 37 (2), 119-122.
@article{article, year = {1996}, pages = {119-122}, keywords = {MAGE-1, -2 and -3 genes, human malignant melanomas}, journal = {Croatian Medical Journal}, volume = {37}, number = {2}, issn = {0353-9504}, title = {Expression of MAGE-1, -2 and -3 genes in primary and metastatic lesions of human malignant melanomas}, keyword = {MAGE-1, -2 and -3 genes, human malignant melanomas} }
@article{article, year = {1996}, pages = {119-122}, keywords = {MAGE-1, -2 and -3 genes, human malignant melanomas}, journal = {Croatian Medical Journal}, volume = {37}, number = {2}, issn = {0353-9504}, title = {Expression of MAGE-1, -2 and -3 genes in primary and metastatic lesions of human malignant melanomas}, keyword = {MAGE-1, -2 and -3 genes, human malignant melanomas} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus





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