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Pregled bibliografske jedinice broj: 475793

Lipid status, paraoxonase-1 activity and metabolic parameters in serum of heifers and lactating cows related to oxidative stress


Antončić-Svetina, Maja; Turk, Romana; Svetina, Ante; Gereš, Darko; Rekić, Branka; Juretić, Dubravka
Lipid status, paraoxonase-1 activity and metabolic parameters in serum of heifers and lactating cows related to oxidative stress // Research in veterinary science, 90 (2011), 2; 298-300 doi:10.1016/j.rvsc.2010.05.022 (međunarodna recenzija, članak, znanstveni)


Naslov
Lipid status, paraoxonase-1 activity and metabolic parameters in serum of heifers and lactating cows related to oxidative stress

Autori
Antončić-Svetina, Maja ; Turk, Romana ; Svetina, Ante ; Gereš, Darko ; Rekić, Branka ; Juretić, Dubravka

Izvornik
Research in veterinary science (0034-5288) 90 (2011), 2; 298-300

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Serum lipids; HDL; paraoxonase-1; oxidative stress; heifers; lactating cows

Sažetak
The objective of this study was to investigate serum lipids, metabolic parameters and activity of the anti-oxidative enzyme paraoxonase-1 (PON1). The study was conducted on non-pregnant heifers with optimal health status and on healthy dairy cows in the period of intensive lactation, assuming that the energy and metabolic demands during lactation reduce anti-oxidative protection. Total cholesterol and HDL-cholesterol concentrations were significantly higher (P<0.05) in lactating cows than in heifers. Bilirubin concentration and γ-glutamyltransferase (GGT) activity were also significantly higher in lactating cows (P<0.05), indicating increased hepatic efforts of cows to meet energy requirements for lactation. Significantly lower PON1 activity and PON1/HDL ratio in lactating cows compared to heifers (P<0.05) showed that metabolic efforts during pregnancy, parturition and lactation influence PON1 activity due to oxidative stress. Concurrent increase in total and HDL-cholesterol during lactation indicated that the HDL particle is a major carrier of cholesterol in cows.

Izvorni jezik
Engleski

Znanstvena područja
Veterinarska medicina



POVEZANOST RADA


Projekt / tema
053-0532052-2046 - Smanjena plodnost u mliječnih goveda (Darko Gereš, )
053-0532265-2231 - Uloga antioksidacijskih enzima i lipoproteina u plodnosti krava i krmača (Ljiljana Bedrica, )

Ustanove
Veterinarski fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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