engleski

Neurodevelopmental outcome of children with intrauterine growth retardation and pathological antenatal color Doppler: a 1-year follow-up

Objective: The aim of the study is to determine the neurodevelopmental outcome of children with IUGR due to placental insufficiency diagnosed by Color Doppler during pregnancy. Patients and methods: 25 children who were diagnosed with IUGR were included. The intrauterine growth was evaluated by repeated US and Doppler examinations and the resistance indexes in umbilical and cerebral fetal blood vessels were registered. The C/U ratio lower than one was considered pathological, implying the phenomena of fetal circulation centralization and brain sparing effect. All children underwent protocol that included the evaluation of other perinatal risk factors and extensive neurological follow-up with repeated brain US, electrophysiological tests, visual and hearing acuity testing, as well as developmental assessment. Results: The gestational age ranged from 30+6 to 41 gestational weeks. The follow-up period ranged from 2 to 16 months. None of the children has severe disorder. Some children have signs of dystonic syndrome (6 cases) or global neurodevelopmental delay (2 cases). The nonoptimal outcome was always connected to neonatal complications and pathological brain US finding (PV-IVH or cortical brain atrophy). Further neurodevelopmental evaluation for assessment og higher cognitive functioning at later (even school age) age will be necessary.

nije evidentirano

nije evidentirano