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Pregled bibliografske jedinice broj: 460856

Genomics in multiple sclerosis


Habek, Mario; Borovečki, Fran; Brinar, Vesna
Genomics in multiple sclerosis // Clinical neurology and neurosurgery (Dutch-Flemish ed.), 112 (2010), 7; 621-624 (međunarodna recenzija, pregledni rad, znanstveni)


CROSBI ID: 460856 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Genomics in multiple sclerosis

Autori
Habek, Mario ; Borovečki, Fran ; Brinar, Vesna

Izvornik
Clinical neurology and neurosurgery (Dutch-Flemish ed.) (0303-8467) 112 (2010), 7; 621-624

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
multiple sclerosis; biomarkers; genomics; microarrays

Sažetak
Multiple sclerosis (MS) is chronic, inflammatory disease of the central nervous system that mainly affects young adults and is characterized with demyelination. It is well known that MS is very heterogeneous disease, so biomarkers that would reliably determine disease course, outcome or treatment response in early stages of the disease (preferentially clinically isolated syndrome) are desperately needed. Genomic analysis of expression profiles represents the profile or imprint of all genes in certain tissue or cell population in certain time point. As human genome is entirely known, it is possible to analyze any given human gene in any given context. This review will discuss results and possible applications of gnome-wide expression studies in brain tissue and blood samples of MS patients.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Projekt / tema
108-0131484-0032 - Sustav poremećaja kortikalnih funkcija u neurološkim bolestima (Zdenko Mubrin, )
108-1081874-1923 - Genomska analiza transkriptoma i interaktoma u bolesnika s kompleksnim bolestima (Fran Borovečki, )
108-1081874-1988 - Molekularne i biološke osnove demijelinizacijskih bolesti živčanog sustava (Vesna Brinar, )

Ustanove
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Profili:

Avatar Url Fran Borovečki (autor)

Avatar Url Vesna Brinar (autor)

Avatar Url Mario Habek (autor)

Citiraj ovu publikaciju

Habek, Mario; Borovečki, Fran; Brinar, Vesna
Genomics in multiple sclerosis // Clinical neurology and neurosurgery (Dutch-Flemish ed.), 112 (2010), 7; 621-624 (međunarodna recenzija, pregledni rad, znanstveni)
Habek, M., Borovečki, F. & Brinar, V. (2010) Genomics in multiple sclerosis. Clinical neurology and neurosurgery (Dutch-Flemish ed.), 112 (7), 621-624.
@article{article, year = {2010}, pages = {621-624}, keywords = {multiple sclerosis, biomarkers, genomics, microarrays}, journal = {Clinical neurology and neurosurgery (Dutch-Flemish ed.)}, volume = {112}, number = {7}, issn = {0303-8467}, title = {Genomics in multiple sclerosis}, keyword = {multiple sclerosis, biomarkers, genomics, microarrays} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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